|
|
|
| Clinical Value of the Diagnosis of Autoimmune Diseases by Antinuclear Antibody Combined and Antinuclear Antibody |
| ZHANG Binbin, WANG Feng, GUO Wei, et al |
| The Affiliated Hospital of Chengde Medical College, Hebei Chengde 067000, China |
|
|
|
|
Abstract Objective: To analyze and explore the clinical value of combined detection of antinuclear antibodies and antinuclear antibodies in the diagnosis of autoimmune diseases. Method: 1103 blood samples were submitted to our hospital, antinuclear antibody detection and antinuclear antibody spectrum detection were simultaneously tested. Antinuclear antibodies were detected by indirect immunofluorescence, and antinuclear antibodies were detected by Western blot. The data of patients with positive results were collected and analyzed statistically. Results: The positive results of antinuclear antibody test accounted for 6.32% of all patients, and the diagnosis accuracy was 78.21%; Detection of antinuclear antibody spectrum of blood test positive patients accounted for 4.78% of all patients, the diagnosis results showed that antinuclear antibody spectrum diagnosis rate was 91.32%, and the two methods were both positive patients for inspection, found that the highest accuracy is 94.67%. Conclusion: Simultaneous detection of antinuclear antibodies and antinuclear antibody spectrum can effectively improve the accuracy of the detection results, and is worthy of promotion.
|
|
|
|
|
|
[1] 周莲,符明昌,羊文芳,等.抗核抗体和抗核抗体谱联合检测诊断自身免疫性疾病的临床价值[J].海南医学,2016,27(18):2965~2968.
[2] 李艳,孙家祥,鄂建飞,等.1725例血清抗核抗体及抗核抗体谱检测结果分析[J].西部医学,2012,24(3):584~586.
[3] 高仕萍,杨文勇,资云菊,等.抗核抗体和抗核抗体谱联合检测在自身免疫性疾病诊断中的临床应用价值[J].检验医学与临床,2014,(2):222~223.
[4] 郑金菊,牟晓峰.抗核抗体核型检测与特异性抗核抗体谱检测的对比分析[J].国际检验医学杂志,2014,(20):2813~2815.
[5] 姜邦蓉,古兰谦,闫河,等.1130例血清抗核抗体与抗核抗体谱联合检测结果分析[J].现代诊断与治疗,2013,24(6):1315~1316.
[6] 陆俊忠,付启云,张迎梅,等.抗核抗体、抗ENA抗体谱联合检测对系统性红斑狼疮的诊断意义[J].江苏医药,2011,37(24):2999~3000.
[7] 代方英.自身免疫性疾病检查抗核抗体与可提取的核抗原谱的临床意义[J].中国医药指南,2012,10(4):160~161. |
|
|
|
2017, Vol. 23 
