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| Effect of Brinzolamide on Primary Open-angle Glaucoma and Vision Protection |
| QIU Manchun, YAN Wenjing, YANG Xuelian, et al |
| Panzhihua Central Hospital, Sichuan Panzhihua 617067, China |
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Abstract Objective: To investigate the clinical effects of brinzolamide treatment of primary open-angle glaucoma and its effect on the patient's field of vision protection. Methods: 98 cases of primary open-angle glaucoma patients were randomly divided into control group and observation group, 49 cases in each group. Patients in the control group were treated with conventional symptomatic treatment .Patients in the observation group rnderwent treatment of brinzolamide based on the control group. Results: After treatment, MD in the observation group patients compared with before treatment were decreased, the difference was statistically significant (P <0.05). After treatment, MD and average visual field defects variance in the observation group patients were lower than the control group, while MS in the observation group patients were higher than the control group, the difference was statistically significant (P <0.05). Conclusion: Brinzolamide treatment of primary open-angle glaucoma can effectively protect patient vision, control visual field defect and reduce the variance of visual field defect, improve patient quality of life.
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[1] 曹芃,孟庆刚,郭月英.益脉康片改善青光眼视野缺损的临床观察[J].新疆中医药,2011,29(5):7~9.
[2] Inoue K,Masumoto M,Wakakura M,et al.Ocular hypotensive effect,preservation of visual fields and safety of adding dorzolamide to prostaglandin therapy for twelve months[J].Clin Ophthalmol,2011,5:393~396.
[3] 杨玉霞,刘杏,黄晶晶,等.原发性开角型青光眼小梁网组织早衰的初步研究[J].中山大学学报(医学科学版),2014,35(5):796~800.
[4] 梁庆丰,刘旭阳.北京眼压与颅压相关疾病研究中跨筛板压力差致青光眼视神经损伤的机制[J].中华眼科杂志,2014,50(10):798~800.
[5] 何翠蓉,伍帆.透明质酸钠在青光眼小梁切除术中的应用[J].西部医学,2010,22(4):727~728.
[6] Fujishiro T,Mayama C,Aihara M,et al.Central 10- degree visual field change following trabeculectomy in advanced openangle glaucoma[J].Eye(Lond),2011,25(7):866~871.
[7] 汤丹.噻吗洛尔与卡替洛尔治疗原发性开角型青光眼的效果及安全性分析[J].医学综述,2014,20(13);2469~2470.
[8] 彭洁,罗谦,程依琏,等.酒石酸溴莫尼定0.15％滴眼液治疗开角型青光眼及高眼压症的临床研究[J].中华眼外伤职业眼病杂志,2014,36(8):569~573.
[9] 戴涛,秦书娟,赵钰,等.真空小梁成形术治疗开角型青光眼及高眼压症[J].中华眼外伤职业眼病杂志,2014,36(7):541~543. |
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2017, Vol. 23 
