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| Clinical Value of Serum Procalcitonin and C-reactive Protein on Middle-aged and Elderly Chronic Obstructive Pulmonary with Acute Aggravating Concurrent Infection |
| WANG Lijun |
| Yuquan Hospital Affiliated of Tsinghua university, Beijing 100049, China |
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Abstract Objective: To explore the clinical value of serum procalcitonin and C-reactive protein on middle-aged and elderly chronic obstructive pulmonary with acute aggravating concurrent infection. Methods: 127 cases patients of chronic obstructive pulmonary disease met the inclusion criteria were chose in our hospital from December 2014 to April 2016, according to patient's condition, divided the COPD disease remission group(remission group) and COPD acute aggravating group (aggravating group). Then subdivided into COPD with acute aggravating infection group (infection group) and COPD with acute aggravating infection-free group (infection-free group) at the COPD acute aggravating group, infection group was graded according to the patient's lung function. The different level of serum PCT and CRP on different grouping and classification were compared. Results: The levels of CRP and serum PCT at COPD acute aggravating group was significantly higher than those in stable phase (P <0.05). The level of PCT and CRP at COPD with acute aggravating infection group was significantly increased than infection-free group (P <0.05). The level of PCT and CRP at level Ⅰ, Ⅱ, Ⅲ lung grade function of COPD with acute aggravating infection group, showed a gradual upward trend, and the statistical difference was significant between different classification (P <0.05). Conclusion: The level of serum PCT and CRP on COPD with acute aggravating infection group are significantly increased, and increase more significantly with the deterioration of lung function.
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2017, Vol. 23 
