|
|
Effect of Dezocine Combined with Ropivacaine on Postoperative Analgesia, Stress Response and the Immune Function of Patients with Gastric Cancer |
LIU Jingyu, MEN Fangli, TIAN Xiaopeng, et al |
The People's Hospital of Dongying, Shandong Dongying 257091, China |
|
|
Abstract Objective: To explore the effects of Dezocine combined with Rropivacaine on postoperative analgesia, stress response and the immune function of patients with gastric cancer. Methods: 74 cases of gastric cancer patients in our hospital undergone surgery were divided into dezocine combined with ropivacaine group (study group) and fentanyl ropivacaine group (control group) according to different drugs used by the patients. Postoperative analgesia, stress reaction and immune function of the two groups were compared. Results: 4h, 8h, 24h and 48h after the operation, the scale scores of the patients from visual fuzzy scale (VAS) in the study group were significantly lower than those in the control group (P<0.05). 4h, 8h and 24h after the operation, the levels of ET and AngⅡin the study group were significantly lower than those in the control group (P<0.05). 24h after the operation, the levels of CD3, CD4 and NK cells in the study group were significantly higher than those in the control group (P<0.05). The total adverse reactions after the operation in the study group were significantly lower than those in the control group (P<0.05). Conclusion: Dezocine combined with Ropivacaine has better analgesia effect in postoperative patients with gastric cancer, can reduce patients' stress response level and enhance patients' immune function,whose clinical effect is better.
|
|
|
|
|
[1] 李然, 许幸. 地佐辛注射液用于缓解术后疼痛的有效性和安全性[J].中国临床药理学杂志,2014,30(1):3~5. [2] 周攀科.地佐辛用于术后镇痛的研究进展[J].实用医院临床杂志,2011,8(6):169~172. [3] 艾玲,徐卉,鲁佩,等.地佐辛静脉自控镇痛对肺叶切除术后炎症反应的影响及镇痛效果的评价[J].华中科技大学学报:医学版,2014,42(4):413~416. [4] 万利芹,陈宇,周巧林,等.右美托咪定复合亚麻醉剂量氯胺酮对开胸术患者麻醉恢复期躁动的影响[J].中华麻醉学杂志,2015,35(2):161~164. [5] 吴江东,蒋宗滨.术后镇痛的趋势—多模式镇痛[J].实用疼痛学杂志,2013,2(9):63~67. |
|
|
|