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| Diagnostic Value and Imaging Features of Retinoblastoma (Rb) on MSCT and MRI |
| JIANG Shijie, WANG Li, ZHANG Hui, et al |
| Xi'an People's Hospital / The Fourth Hospital of Xi'an, Shaanxi Xi'an 710004, China |
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Abstract Objective: To compare the diagnostic value of MSCT and MRI in the detection of retinoblastoma (Rb).Methods: A total of 125 suspected Rb patients treated at our hospital from January 2019 to June 2023 were included. MSCT and MRI were performed, with pathological findings used as the gold standard for diagnosis. Sensitivity, specificity, accuracy, and consistency with pathological results were analyzed for both imaging modalities.Results: The positivity rates of Rb detected by MRI, MSCT, and pathology were 44.00% (55/125), 52.80% (66/125), and 45.60% (57/125), respectively, with no statistically significant difference (P>0.05). The Kappa value for MRI compared to pathology was 0.644, lower than the Kappa value of 0.729 for MSCT. The sensitivity of MRI (78.94%) was lower than that of MSCT (92.98%), with a statistically significant difference (P<0.05). The specificity of MRI (85.29%) was higher than that of MSCT (80.88%), while the accuracy of MRI (82.40%) was lower than that of MSCT (86.40%), but these differences were not statistically significant (P>0.05). MSCT showed irregular thickening of the eyeball wall, irregular nodular soft tissue density in the vitreous cavity, and patchy calcifications within the lesion. MRI revealed uneven thickening of the eyeball ring, irregular mass-like abnormal signal shadows in the vitreous cavity, iso-intense signal on T1-weighted imaging (T1WI), slightly hyper-to hypo-intense mixed signal on T2-weighted imaging (T2WI), and heterogeneous enhancement on contrast-enhanced scans.Conclusion: Compared to MRI, MSCT demonstrates higher consistency with pathological findings and higher sensitivity in detecting Rb, indicating superior diagnostic value.
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2024, Vol. 30 
