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| Clinical Characteristics of Patients with Early Psoriatic Arthritis and Bone Erosion |
| ZHANG Ying, WANG Junxiang |
| Hebei Medical University Third Hospital, Hebei Shijiazhuang 050051, China |
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Abstract Objective: To explore the clinical characteristics and related factors of patients with early Psoriatic Arthritis (PsA) who develop bone erosion.Methods: Fifty patients with early PsA (disease duration ≤ 1 year) hospitalized from January 2018 to January 2023 were selected. Peripheral joints of patients were examined using color Doppler ultrasonography to analyze the location and features of bone erosion. Based on the presence or absence of bone erosion on ultrasound, patients were categorized into the bone erosion group and the non-bone erosion group. The differences in clinical and laboratory parameters, as well as ultrasound images, between the two groups, were analyzed, including age, gender, disease duration, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and others. Results: Among the 50 PsA patients, 23 (46.00%) had bone erosion, while 27 (54.00%) did not. The bone erosion group had involvement of a higher number of peripheral joints compared to the non-bone erosion group (P<0.05). The prevalence of involvement in hand and foot joints and enthesitis was significantly higher in the bone erosion group (P<0.05). No statistically significant differences were found between the two groups in terms of age, gender, disease duration, pre-existing skin rash, axial joint involvement, HLA-B27 positivity, and inflammatory markers (P>0.05). Involvement of hand and foot joints, enthesitis, and the number of affected peripheral joints were positively correlated with bone erosion. Conclusion: Bone erosion is more common in patients with early PsA, most frequently occurring in hand and foot joints, and is closely associated with enthesitis and the number of affected peripheral joints.
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2024, Vol. 30 
