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Application Value of Low-Dose CT in the Diagnosis and Monitoring of Pulmonary Tuberculosis |
WANG Li, GAO Yu, WANG Zhiyong, et al |
Shaanxi Tuberculosis Hospital /The Fifth People's Hospital of Shaanxi Province, Shaanxi Xi'an 710048, China |
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Abstract Objective: To investigate the application value of low-dose CT in the diagnosis and monitoring of pulmonary tuberculosis. Methods: The clinical data of 357 patients who were suspected of pulmonary tuberculosis and treated in the hospital from March 2019 to March 2021 were analyzed retrospectively. All patients underwent conventional-dose and low-dose scanning. The diagnostic performance, detection rates of imaging features, image quality, and radiation parameters were compared between the two scanning methods. Results: Pathological results showed 350 patients with pulmonary tuberculosis, and 342 cases were diagnosed with low-dose scanning. The sensitivity, specificity and accuracy were 99.42%, 33.33% and 96.64%. 344 cases were diagnosed with conventional-dose scanning. The sensitivity, specificity and accuracy were 99.71%, 46.15% and 97.76%. The diagnostic sensitivity, specificity, and accuracy of the two scanning methods were similar (P>0.05). The image quality scores of cross-sectional and coronal lung window and mediastinal window were close in terms of different scanning methods (P>0.05). The detection rates of imaging signs such as lung consolidation, ground-glass opacity and calcification by the two scanning methods were close (P>0.05). The dose-length product, volume CT dose index and effective dose of low-dose scanning were lower than those of conventional-dose scanning (P<0.05). Conclusion: Compared with conventional-dose CT scanning, low-dose CT scanning can effectively reduce radiation dose while achieving comparable diagnostic results and image quality. It can be used for the diagnosis and monitoring of pulmonary tuberculosis.
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