|
|
Clinical Value of Carotid Artery Ultrasound Parameters Combined with Plasma Small and Dense Low-Density Lipoprotein in Evaluating Atherosclerotic Cardiovascular Disease in Diabetic Patients |
SUN Xiaoting, et al |
Linfen Central Hospital, Shanxi Linfen 041000, China |
|
|
Abstract Objective: To investigate the clinical value of carotid artery ultrasound parameters combined with plasma small and dense low-density lipoprotein (sd-LDL) in evaluating atherosclerotic cardiovascular disease (ASCVD) in diabetic patients. Methods: The clinical data of 104 diabetic patients admitted to the hospital from July to December 2022 were analyzed retrospectively. Patients with simple diabetes were defined as the control group (n=51) and those with ASCVD were defined as the observation group (n=53). Carotid artery ultrasound parameters and sd-LDL were compared between groups. Logistic regression analysis was performed to screen the influencing factors of ASCVD in diabetic patients. The clinical value of carotid artery ultrasound parameters and sd-LDL in evaluating ASCVD in diabetic patients was discussed. Results: Carotid artery ultrasound parameters (carotid intima-media thickness (IMT) and plaque score) and sd-LDL level in the observation group were larger/higher than the control group (P<0.05). The numbers of smokers in the two groups were close (P<0.05). Logistic regression analysis found that IMT, plaque score and sd-LDL level were influencing factors of ASCVD in diabetic patients (P<0.05). Conclusion: Carotid artery ultrasound parameters and sd-LDL are much helpful for evaluating ASCVD in diabetic patients. Clinically, combination of IMT and plaque score and sd-LDL level can be adopted to provide a basis for clinical diagnosis and treatment of ASCVD.
|
|
|
|
|
[1] 刘淑党,林静娜,邱慧娜,等.2型糖尿病患者血尿酸水平与发生动脉粥样硬化性心血管疾病事件风险的影响研究[J].中国糖尿病杂志,2022,30(4):241-245. [2] Biswas M,Saba L,Omerzu T,et al.A review on joint carotid intima-media thickness and plaque area measurement in ultrasound for cardiovascular/stroke risk monitoring:artificial intelligence framework[J].Digit Imaging,2021,34(3):581-604. [3] Ikezaki H,Furusyo N,Yokota Y,et al.Small dense low-density lipoprotein cholesterol and carotid Intimal medial thickness progression[J].Atheroscler Thromb,2020,27(10):1108-1122. [4] 林文敏,吴 铿.APE1在糖尿病心肌病中的研究进展[J].海南医学,2020,31(10):1306-1308. [5] 陈云,叶路敏,王文琴,等.幽门螺旋杆菌与冠心病及颈动脉硬化的相关性分析[J].浙江临床医学,2020,22(11):1580-1582. [6] 沙琬婧,柳雨亭,瞿惠燕,等.小而密低密度脂蛋白在冠心病中西医治疗中的研究进展[J].中西医结合心脑血管病杂志,2021,19(16):2768-2770. [7] 陈伟,黄明,高航.糖尿病患者颈动脉超声参数与FRS评分在评估动脉粥样硬化性心血管疾病中的价值[J].中国循证心血管医学杂志,2022,14(3):330-332. [8] Hoogeveen RC,Gaubatz JW,Sun W,et al.Small dense low-density lipoprotein-cholesterol concentrations predict risk for coronary heart disease:the atherosclerosis risk in communities (ARIC] study[J].Arterioscler Thromb Vasc Biol,2014,34(5):1069-1077. [9] 范雪松,莘琳琳,胡荣,等.小而密低密度脂蛋白胆固醇与动脉粥样硬化性心血管疾病相关性的研究进展[J].中华预防医学杂志,2021,55(12):1507-1512. [10] 陈雅斌,蔡禾辉,张建明,等.血浆小而密低密度脂蛋白与缺血性脑卒中的相关性[J].检验医学,2020,35(5):409-413. |
|
|
|