|
|
|
| Analysis of the Effects of Complete Endoscopic Radical Thyroidectomy with Non-Pneumatic Axillary Approach on Parathyroid Function and Related Hormone Levels |
| LING Yao, LAN Xuejun, et al |
| West China Hospital,Sichuan University, Sichuan Chengdu 610041, China |
|
|
|
|
Abstract Objective: To investigate the effect of complete endoscopic radical thyroidectomy (GUA) with non-pneumatic axillary approach on parathyroid function and related hormone levels. Methods: A total of 116 patients with thyroid cancer in our hospital from January 2020 to January 2022,and the enrolled patients were divided into a endoscopic group of 58 cases and an open group of 58 cases using a random number table method.The endoscopic group was treated with GUA surgery,and the open group was treated with radical neck anterior incision.The changes of perioperative indexes,postoperative complications,and VAS of patients in the two groups were recorded at 24h and 48h after operation; changes in thyroid hormone levels before and 3 days after surgery. Results: Intraoperative blood loss was less in the endoscopic group than in the open group,the duration of surgery was longer in the endoscopic group than in the open group,the postoperative drainage was higher in the endoscopic group than in the open group,and the postoperative hospital stay was shorter in the endoscopic group than in the open group (P<0.05).There was no significant difference in postoperative complications between the two groups (P>0.05).VAS scores were lower in the endoscopic group than in the open group at 24h and 48h.PTH,T3 and T4 levels were lower than preoperative levels,while TSH levels were higher in the two groups at 1 month postoperatively (P<0.05); the difference in PTH,T3,T4 and TSH levels before and after surgery was lower in the laparoscopic thyroid cancer patients than in the control group (P<0.05). Conclusion: The GUA procedure for patients with thyroid cancer has a low impact on parathyroid function and is worthy of clinical consideration.
|
|
|
|
|
|
[1] Jensen CB,Pitt SC.Patient perception of receiving a thyroid cancer diagnosis[J].Curr Opin Endocrinol Diabetes Obes,2021,28(5):533-539.
[2] Cai X,Wang R,Tan J,et al.Mechanisms of regulating NIS transport to the cell membrane and redifferentiation therapy in thyroid cancer[J].Clin Transl Oncol,2021,23(12):2403-2414.
[3] 张斌.无充气腋窝入路完全腔镜下甲状腺癌根治术安全性及可行性研究[J].辽宁医学杂志,2020,34(1):39-41.
[4] 郑传铭,毛晓春,王佳峰,等.无充气腋窝入路完全腔镜下甲状腺癌根治术效果初步评价初期体会[J].中国肿瘤临床,2018,45(1):27-32.
[5] Baink GL,Shindo ML,Kraimer KL,et al.Prevalence and risk factors for multifocality in pediatric thyroid cancer[J].JAMA Otolaryngol Head Neck Surg,2021,147(12):1100-1106.
[6] 杜德良,王红.全腔镜甲状腺癌根治术与传统开放手术的临床效果分析[J].腹腔镜外科杂志,2022,27(6):406-409.
[7] 贾高磊,田志龙,耿厚法,等.无充气腋窝入路完全腔镜下甲状腺手术意外出血的处理[J].中国微创外科杂志,2022,28(7):570-574.
[8] 项洋锋,赏金标,王文栋,等.两种入路无充气腔镜甲状腺手术与颈前入路甲状腺手术对比分析[J].肿瘤学杂志,2021,27(4):316-318.
[9] 许世莹,王培恩,缪贝贝,等.无充气腋窝入路完全腔镜手术在低危甲状腺乳头状癌患者中的应用研究[J].浙江大学学报(医学版),2021,50(6):716-721. |
|
|
|
2023, Vol. 29 
