|
|
|
| Correlation Analysis of Stone and Urine Composition and Stone Recurrence in Patients with Urinary Calculi |
| HU Xiaojian, ZHENG Liang, ZHANG Zhigang, et al |
| The Second Affiliated Hospital of Xi'an Medical College, Shaanxi Xi'an 710038, China |
|
|
|
|
Abstract Objective: To investigate the correlation between stone and urine composition and stone recurrence in patients with urinary calculi. Methods: A total of 120 patients with urinary calculi were treated in the hospital from March 2019 to May 2021.They were selected as the research subjects,and followed up for 1 year.The postoperative stone recurrence rate was recorded.The patients were grouped according to the presence or absence of stone recurrence.General clinical data of the patients were analyzed to screen the risk factors for stone recurrence.The correlation between stone and urine composition and stone recurrence was analyzed. Results: Among the 120 patients,27 patients had stone recurrence,and the 1-year recurrence rate was 22.50%.The proportion of patients aged 70 or older in the recurrence group (62.96%) was higher than that in the non-recurrence group (40.86%).The proportion of surgical stone removal rate ≥80% in the recurrence group (66.67%) was lower than that in the non-recurrence group (90.32%).The proportion of patients with history of endocrine diseases in the recurrence group (55.56%) was higher than that in the non-recurrence group (21.50%) (P<0.05).The pH value of urine components in the recurrence group (5.36±0.58) was lower than that in the non-recurrence group (6.89±0.71).The levels of uric acid,oxalic acid and phosphorus[(2.67±0.26) mmoL/L,(0.52±0.05) mmoL/L and (15.49±2.47) mmoL/L] were higher than those in the non-recurrence group[(2.15±0.28) mmoL/L,(0.41±0.06) mmoL/L and (12.36±2.38) mmoL/L] (P<0.05).The proportion of magnesium ammonium phosphate in the recurrence group (66.67%) was higher than that in the non-recurrence group (23.66%) (P<0.05).Logistic regression analysis showed that age ≥ 70,history of endocrine disease,magnesium ammonium phosphate in stone composition,surgical stone clearance rate <80%,urine pH value,uric acid,oxalic acid,and phosphorus were risk factors for stone recurrence in patients with urinary calculi.Correlation analysis showed that magnesium ammonium phosphate in the stone components was positively correlated with the recurrence of stones (r=0.536,P<0.05),pH in urine components was negatively correlated with the recurrence of stones (r=-0.417,P<0.05),and uric acid,oxalic acid and phosphorus were positively correlated with the recurrence of stones (r=0.387,0.425,0.439,P<0.05). Conclusion: Patients with urinary calculi have a relatively high rate of postoperative stone recurrence,especially those aged ≥ 70,with history of endocrine disease,with magnesium ammonium phosphate in stone composition,with surgical stone clearance rate < 80%,lower urine pH,lower urine uric acid,oxalic acid and phosphorus.Clinically,treatment for the above patients should be strengthened to reduce the risk of stone recurrence.
|
|
|
|
|
|
[1] 王友铭,许长宝,王晓甫,等.河南省泌尿系结石住院患者流行病学特点及分析[J].临床泌尿外科杂志,2021,36(6):458-463.
[2] 聂元鹏,唐喜香,李海成,等.2型糖尿病患者腹型肥胖程度与结石患病风险的相关性分析[J].中华糖尿病杂志,2020,12(3):181-185.
[3] 王静,李凡.输尿管结石患者术后发生泌尿道感染的logistic分析[J].中国卫生统计,2020,37(5):740-741.
[4] 王贵林.体外碎石联合中药排石治疗泌尿系结石的临床效果[J].中国医药导报,2021,18(15):88-91.
[5] 李剑,曹景宏,陈欣.基于结石成分分析和尿液理化性质检测与饮食干预对预防泌尿系结石复发的探讨[J].中国预防医学杂志,2020,21(9):1063-1066.
[6] 冯丽丽,陆婷,周珊,等.糖尿病患者尿路结石成分特点及其形成的危险因素分析[J].长春中医药大学学报,2021,37(3):586-589.
[7] 李国平,李道源,刘元晓,等.经皮肾镜取石术后泌尿系感染病人结石复发的相关因素分析[J].实用老年医学,2021,35(9):931-934.
[8] 邱晓东,朱东风,李永廉,等.代谢综合征与泌尿系统结石成分及危险因素相关性分析[J].广东医学,2019,40(14):2063-2066.
[9] 祝秀文,童炎岳,万里军,等.清热补肾排石方对上尿路结石患者PCNL术后残石排出及尿液成分的影响[J].中国性科学,2020,29(4):121-124. |
|
|
|
2023, Vol. 29 
