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| Value of PCT and hs-CRP Combined with Clinical Pulmonary Infection Score in Prognosis Evaluation of Elderly Patients with Severe Pneumonia |
| WANG Yilv, WANG Zhen, ZHONG Wen, et al |
| Chengdu Third People's Hospital, Sichuan Chengdu 610000, China |
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Abstract Objective: To observe the clinical value of serum procalcitonin (PCT) and high-sensitivity C-reactive protein (hs-CRP) combined with clinical pulmonary infection score (CPIS) in prognosis evaluation of elderly patients with severe pneumonia (SP). Methods: This study included 92 elderly patients with severe pneumonia (severe group) and 30 elderly patients with ordinary pneumonia (ordinary group) who were admitted to the hospital from April 2020 to March 2022, and 30 elderly patients without major diseases (control group). Serum PCT and hs-CRP levels, and CPIS were compared among the groups. According to the survival status within 1 month after admission, patients in the severe group were divided into a survival group and a death group. Serum PCT and hs-CRP levels, and CPIS in patients with different prognoses were observed. The receiver operating characteristic (ROC) curve was used to analyze the prognostic value of serum PCT, and hs-CRP combined with CPIS in elderly patients with SP. Results: Serum PCT and hs-CRP levels, and CPIS in the severe group at admission were significantly higher than those in the ordinary group and the control group (P<0.05). Serum PCT and hs-CRP levels, and CPIS in the death group were significantly higher than those in the survival group (P<0.05). ROC curve analysis showed that the best cut-off values of serum PCT, hs-CRP, and CPIS were 9.595ng/mL, 17.615mg/L, and 8.175. All three could be used for the prognosis of elderly patients with SP (P<0.05). The sensitivity of the combination of the three in the prognosis of elderly patients with SP was higher than that of each index (P<0.05). Conclusion: Compared with patients with ordinary pneumonia and healthy elderly people, elderly patients with SP have higher serum PCT and hs-CRP levels, and higher CPIS. Combined detection of the three is of high value in the prognosis of elderly patients with SP. Therefore, close monitoring of the three indicators is recommended in clinical practice.
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2023, Vol. 29 
