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Analysis of Preoperative Blood Lipid Levels and Coronary Artery Disease Syntax Score in Postmenopausal Women with ACS Undergoing PCI |
ZHENG Chunhua, ZHOU Jiang, GUO Jingtao, et al |
Chengde Central Hospital, Hebei Chengde 067000, China |
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Abstract Objective: To investigate the status of preoperative blood lipid levels and the Syntax score of coronary artery lesions in postmenopausal women with acute coronary syndrome (ACS) patients undergoing coronary intervention, so as to provide a favorable basis for clinical treatment.Methods: A total of 126 postmenopausal female ACS patients who underwent interventional therapy in our hospital from June 2020 to June 2021 were selected and divided into control group (34 cases of acute ST-segment elevation myocardial infarction) and observation group (92 cases of acute coronary syndrome with non-ST segment elevation), the changes of preoperative blood lipid levels in the two groups of patients were analyzed, and the Syntax score of coronary artery lesions in the two groups of patients was also analyzed. Results: There were significant differences in menopause age, history of hypertension, diabetes history, smoking history, TC and TG indexes in the observation group (P<0.05). There was no significant difference in HDL-C, LDL-C level stratification and Syntax score between the two groups (P>0.05). In the control group, the level of LP(a) in severe lesions was higher than that in mild and moderate lesions, and the level of LP(a) in moderate lesions was higher than that in mild lesions, and the differences were statistically significant (P<0.05). However, in the observation group, the levels of LDL-C, LP(a) and TG in the severe lesions were higher than those in the mild and moderate lesions, and the levels of LDL-C, LP(a) and TG in the moderate lesions were higher than those in the mild lesions. Statistical significance (P<0.05). Apolipoprotein B/Apolipoprotein Al (APOB/APOAI) in the severe lesion was higher than that in the mild and moderate lesions, and the difference was statistically significant (P<0.05). Conclusion: In the treatment of postmenopausal women with acute coronary syndrome by coronary intervention, the more important blood lipid indicators are APOB/APOAI, LP(a), LDL-C, and TG, which should be further studied in clinical practice to provide an effective basis for treatment.
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