NLR MAGE PNI预测解剖性肝切除术后并发腹腔感染的临床价值

doi:10.3969/j.issn.1006-6233.2022.09.021

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Abstract Objective: To explore the clinical value of the neutrophil-to-lymphocyte ratio (NLR), mean amplitude of glycemic excursions (MAGE), and prognostic nutritional index (PNI) in predicting the intra-abdominal infection after anatomical hepatectomy. Methods: 192 patients who underwent anatomical hepatectomy in the hospital were selected between October 2018 and October 2021, including 43 patients with postoperative intra-abdominal infection (infected group) and 149 patients without intra-abdominal infection (non-infected group). All patients received routine blood examination and blood glucose monitoring within 3 d before surgery. The NLR, MAGE, and PNI were calculated and the differences between groups were analyzed. The receiver operating characteristic curve (ROC curve) was used to evaluate the value of the three indicators for predicting the postoperative intra-abdominal infection. Results: There were statistical differences between the infection group and the non-infected group in terms of the presence of diabetes mellitus, surgical time, and indwelling time of the intra-abdominal drainage tube (P<0.05). NLR, MAGE, and PNI in the infected group before surgery were significantly higher than those in the non-infected group (P<0.05). The areas under the ROC curves of NLR and MAGEPNI for predicting intra-abdominal infection after anatomical hepatectomy were 0.825 (95%CI:0.763~0.876), 0.957 (95%CI:0.918~0.981) and 0.914 (95%CI:0.865~0.949) respectively, with good predictive efficiency. Logistics regression analysis showed that the presence of diabetes mellitus, surgical time≥ 5h, drainage tube indwelling time≥3d, NLR>2.35, MAGE>0.83, and PNI>43.79 were the risk factors for intra-abdominal infection after anatomical hepatectomy (P<0.05). Conclusion: Preoperative NLR, MAGE, and PNI have certain predictive value on postoperative intra-abdominal infection in patients with anatomical hepatectomy, and can provide a reference for clinical prevention and treatment.

Key words： Neutrophil-to-lymphocyte ratio Mean amplitude of glycemic excursions Prognostic nutritional index Anatomical hepatectomy Intra-abdominal infection

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2022.09.021 OR http://www.hbyxzzs.cn/EN/Y2022/V28/I9/1511

[1] 李云峰,尹新民.腹腔镜解剖性肝切除手术主刀模式变迁及优化[J].中华消化外科杂志,2019,18(5):430-433.
[2] 倪争艳,费卫珠,张伊.肝癌患者外科切除术后感染风险预测模型的建立[J].中国感染控制杂志,2021,20(7):614-618.
[3] 姜霞,谷申森,芦雪萍,等.肝癌患者手术前后清蛋白水平对术后腹腔感染的影响[J].国际检验医学杂志,2021,42(22):2706-2709,2713.
[4] 汪赛,梁朝朝,周骏,等.中性-淋巴细胞比和预后营养指数在膀胱癌根治术患者预后评估中的价值[J].安徽医科大学学报,2019,54(4):640-646.
[5] 张明城,邓克非,何其英.预后营养指数对膀胱癌患者根治术后感染的预测价值[J].重庆医学,2021,50(9):1536-1540.
[6] 中华人民共和国卫生部.医院感染诊断标准(试行)[J].现代实用医学,2003,81(7):460-465.
[7] 中华医学会外科学分会,中国研究型医院学会感染性疾病循证与转化专业委员会,中华外科杂志编辑部.外科常见腹腔感染多学科诊治专家共识[J].中华外科杂志,2021,59(3):161-178.
[8] 张晓,王亚东,徐宗全,等.肝癌切除术后患者腹腔感染的病原学和耐药性及影响因素分析[J].中华医院感染学杂志,2019,29(14):2149-2153.
[9] 潘熠平,胡军涛,赖洁,等.外科ICU重症腹腔感染的临床特征及病原菌流行病学分析[J].中华危重病急救医学,2020,32(7):792-796.
[10] 唐孝良,王亚儒,姚远,等.NLR、FIB和Pgp1评估结直肠癌预后的价值[J].中国现代医学杂志,2018,28(32):112-116.
[11] 符小婧,何书杏,苏连红,等.糖尿病专用肠内营养制剂对胃癌术后病人应激性血糖波动和胰岛素抵抗的影响[J].肠外与肠内营养,2021,28(4):225-229.
[12] 戴凌燕,程碧环,李军.血糖波动幅度对术后严重腹腔感染患者预后的评估价值[J].中华全科医学,2015,13(11):1791-1793.
[13] 郭孟刚,周海宁,杨绪全.预后营养指数评估食管癌病人术后并发症及预后的临床价值[J].安徽医药,2021,25(5):898-902.