老年冠心病心力衰竭患者血清脑钠肽C反应蛋白与心肌损伤程度及心功能的相关性分析

doi:10.3969/j.issn.1006-6233.2022.05.013

Abstract
Figure/Table
References
Related Citation (15)

Download: PDF (1214 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective: To analyze the correlation of serum brain natriuretic peptide (BNP), and C-reactive protein (CRP) with the severity of myocardial injury and cardiac function in elderly patients with coronary heart disease and heart failure. Methods: A total of 106 elderly patients with coronary heart disease and heart failure admitted to Suining Central Hospital were selected between January 2019 and January 2021. The levels of serum BNP, cardiac troponin I (cTnI) and CRP were detected, and correlation analysis was conducted. Results: Serum BNP, CRP and cTnI levels of the patients enrolled were (578.09±46.17) g/ml, (7.07±1.85) mg/l and (0.050±0.011) ng/ml. Correlation analysis showed that serum BNP and CRP levels were positively correlated with cTnI (P<0.05). There were statistically significant differences in serum BNP and CRP levels between patients with different grades of heart failure (P<0.05). Serum BNP and CRP levels of patients with gradeⅠ~Ⅱ heart failure were significantly lower than those of patients with grade Ⅲ and grade Ⅳ (P<0.05). Serum BNP and CRP levels of patients with grade Ⅲ heart failure were significantly lower than those of patients with grade IV (P<0.05). Serum BNP, cTnI and CRP levels were positively correlated with cardiac function classification (P<0.05). Conclusion:Serum BNP, cTnI and CRP levels are correlated with heart failure in elderly patients with coronary heart disease, when serum BNP, cTnI, and CRP levels are significantly increased, it is necessary to be alert to the aggravation of myocardial injury and the increase of cardiac function.

Key words： Coronary heart disease Heart failure Severity of myocardial damage Cardiac function Serum brain natriuretic peptide C-reactive protein Cardiac troponin

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	YANG Liping
	MA Junjie
	HOU Bin
	et al

Cite this article:

YANG Liping,MA Junjie,HOU Bin, et al. Correlation of Serum BNP and CRP with the Severity of Myocardial Injury and Cardiac Function in Elderly Patients with Coronary Heart Disease and Heart Failure[J]. HeBei Med, 2022, 28(5): 763-765.

URL:

http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2022.05.013 OR http://www.hbyxzzs.cn/EN/Y2022/V28/I5/763

[1] Boorsma EM,Ter Maaten JM,Damman K,et al.Congestion in heart failure:a contemporary look at physiology,diagnosis and treatment[J].Nat Rev Cardiol,2020,17(10):641~655.
[2] Liang F,Wang Y.Coronary heart disease and atrial fibrillation:a vicious cycle[J].Am Physiol Heart Circ Physiol,2021,320(1):1~12.
[3] Pagliaro BR,Cannata F,Stefanini GG,Bolognese L.Myocardial ischemia and coronary disease in heart failure[J].Heart Fail Rev,2020,25(1):53~65.
[4] 中华医学会心血管病学分会心力衰竭学组,中国医师协会心力衰竭专业委员会,中华心血管病杂志编辑委员会.中国心力衰竭诊断和治疗指南2018[J].中华心血管病杂志,2018,46(10):760~789.
[5] Kayali S,Ertugrul I,Yoldas T,et al.Sensitive cardiac troponins:could they be new biomarkers in pediatric pulmonary hypertension due to congenital heart diseasep[J] Pediatr Cardiol,2018,39(4):1~8.
[6] 段威,张莹.美托洛尔联合曲美他嗪在冠心病心力衰竭治疗中的应用分析[J].贵州医药,2021,45(3):388~389.
[7] 陈鑫龙,田晶,张青,等.冠心病慢性心力衰竭病人住院前后血清NT-proBNP、cTnI、sST2、GDF-15变化及其影响因素[J].中西医结合心脑血管病杂志,2021,19(10):1622~1626.
[8] 豆书梅,刘美霞,谢飞飞,等.血清降钙素原及C反应蛋白在老年慢性心力衰竭合并肺部感染患者中的应用价值[J].中华老年心脑血管病杂志,2019,21(8):797~800.
[9] Oikonomou E,Zografos T,Papamikroulis GA,et al.Biomarkers in atrial fibrillation and heart Failure[J].Curr Med Chem,2019,26(5):873~887.
[10] 王际军.血清BNP、CTnI水平与老年冠心病心力衰竭患者心肌能量消耗的相关性[J].中国老年学杂志,2020,40(15):3147~3150.
[11] 赵云,郭伟民,安国霞,等.血清脑钠肽、心肌肌钙蛋白I水平变化与慢性心力衰竭患者心功能分级的关联性分析[J].中国临床实用医学,2018,9(1):47~49.
[12] 冯星源,陈谦,关义健.NT-proMPT、CTnI、C-反应蛋白联合检测对急性心力衰竭患者预后评价价值研究[J].河北医药,2019,41(2):215~218.