保留与切除子宫对绝经期子宫脱垂患者盆底肌电性激素尿动力学参数的影响

doi:10.3969/j.issn.1006-6233.2022.03.020

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Abstract Objective: To explore the effects of uterine preservation and removal on pelvic floor electromyography, sex hormones and urodynamic parameters in patients with menopausal uterine prolapse. Methods: A total of 100 patients with menopausal uterine prolapse in our hospital from May 2015 to May 2019 were selected and divided into uterine removal group (n=50) and uterine preservation group (n=50) according to the surgical regimens. Vaginal hysterectomy + anterior and posterior vaginal wall repair and simple anterior and posterior vaginal wall repair were performed respectively. Clinical data were observed including the perioperative indicators, complications, recurrence rate and pelvic floor electromyography (rapid contraction, tension contraction value, endurance test value), sex hormone indicators [estradiol (E2), luteinizing hormone (LH), follicle stimulating hormone (FSH)], urodynamic parameters [maximum urethral closure pressure (MUCP), abdominal pressure leaking urine point pressure (ALPP), maximum urethral pressure (MUP)] before and 1 month after operation in the two groups. Results: The operation time of the uterine removal group was longer than that of the uterine preservation group (P＜0.05). There was no significant difference in the amount of blood loss, hospital stay, and time to get out of bed between the two groups (P＞0.05); one month after operation, the values of tension contraction, rapid contraction and endurance in the uterine removal group were higher than those in the uterine preservation group (P＜0.05); one month after operation, the E2 level of the uterine removal group was lower than that of the uterine preservation group, and the levels of LH and FSH were higher than that of the uterine preservation group (P＜0.05); the MUCP, ALPP and MUP of the uterine removal group were higher than those of the uterine preservation group at 1 month after operation (P＜0.05); there was no significant difference in the incidence of complications between the two groups (P>0.05); after 12 months of follow-up, the recurrence rate of the uterine removal group was lower than that of the uterine preservation group (P＜0.05). Conclusion: Simple anterior and posterior vaginal wall repair, vaginal hysterectomy combined with anterior and posterior vaginal wall repair in the treatment of menopausal uterine prolapse patients have equivalent effects in surgical trauma and postoperative recovery. Combined surgery can improve pelvic floor electromyography and urodynamic parameters, and reduce the recurrence rate, but it can have a certain impact on sex hormone levels.

Key words： Pelvic floor reconstruction Uterus preservation Uterus removal Menopause Uterine prolapse Pelvic floor electromyography Sex hormones Urodynamic parameters

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	REN Jun
	ZHOU Xiufen

Cite this article:

REN Jun,ZHOU Xiufen. The Effect of Preservation Versus Removal of the Uterus on Pelvic Floor Electromyography Sex Hormones and Urodynamic Parameters in Patients with Menopausal Uterine Prolapse[J]. HeBei Med, 2022, 28(3): 445-451.

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2022.03.020 OR http://www.hbyxzzs.cn/EN/Y2022/V28/I3/445

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