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| Analysis of the Short-Term Curative Effect of Different Treatment Regimens on Patients with Aneurysm at the M1 Bifurcation of the Middle Cerebral Artery and Their Influence on Postoperative Infection and Recurrence |
| BIN Zaiqing, YIN Dianmin, TANG Qiyong |
| Hunan Provincial Hospital of Traditional Chinese Medicine, Hunan Zhuzhou 412000, China |
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Abstract Objective: To explore the short-term curative effect of different treatment regimens for patients with M1 bifurcation aneurysm of the middle cerebral artery and their influence on postoperative infection and recurrence. Methods: The clinical data of 46 patients with middle cerebral artery M1 bifurcation aneurysm who were treated between February 2015 and February 2020 were retrospectively analyzed. According to the treatment regimens, they were divided into craniotomy group (26 cases) and interventional embolization group (20 cases). The operation-related indicators and short-term efficacy of the two groups were compared. The patients were followed up for 1 year, and the postoperative infection and recurrence were recorded. Results: The operation time, intraoperative blood loss and hospital stay in the interventional embolization group were significantly shorter, and the treatment cost was significantly higher than those in the craniotomy group, and the differences were statistically significant (All P<0.05). At 1 and 3 months after surgery, there was no significant difference in the clinical efficacy between the two groups of patients (All P>0.05). The clinical efficacy of the two groups at 3 months after surgery was significantly better than that at 1 month after surgery, and the difference was statistically significant (All P>0.05); the postoperative infection rate in the craniotomy group was higher than that in the interventional embolization group (15.38% vs 5.00%), while the postoperative recurrence rate was lower than that in the interventional embolization group (0.00% vs 10.00%), but there was no significant difference between groups (All P>0.05). Conclusion: Both craniotomy and interventional embolization for the treatment of middle cerebral artery M1 bifurcated aneurysms have good short-term curative effects. The former has the advantages of lower postoperative recurrence rate and lower treatment cost, and the latter has lower postoperative infection rate and shorter hospitalization. The optimal treatment regimen should be chosen in the clinical setting, taking into account the patient's actual condition and financial situation.
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2022, Vol. 28 
