经鼻高流量氧气湿化疗法在慢性阻塞性肺疾病呼吸衰竭患者中的应用分析

doi:10.3969/j.issn.1006-6233.2022.01.024

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Abstract Objective: To analyze the application effect of nasal high flow oxygen humidification therapy (hfnc) in patients with chronic obstructive pulmonary disease (COPD) and respiratory failure. Methods: The 158 patients with COPD respiratory failure who were treated in our hospital from January 2019 to January 2021 were selected as the research subjects, and they were simply randomly divided into group A and group B, with 79 cases in each group. Group A was treated with low flow oxygen inhalation through nose, and group B was treated with HFNC. The oxygen metabolism, respiration, blood gas analysis and lung function of the two groups before and after treatment were compared, and the clinical efficacy and adverse reactions of the two groups after treatment were compared. Results: There was no significant difference in oxygen metabolism, respiration, blood gas analysis, and lung function between the two groups before treatment (P>0.05); after treatment, compared with before treatment, the levels of VO₂, respiratory frequency, peak airway resistance, airway resistance, PaO₂ were decreased, the levels of CaO₂, DO₂, SaO₂, PaCO₂, FEV1, FVC, PEER were increased in the two groups, and the changes in the indexes of group B were higher, and the difference was significant (P<0.05). The clinical total effective rates of group A and group B were 78.48% and 94.93% respectively, and the difference was significant (P< 0.05). The incidences of epistaxis, dry nose and dry mouth in group A were higher than those in group B (P< 0.05). Conclusion: Compared with traditional nasal low flow oxygen inhalation therapy, HFNC can effectively improve oxygen metabolism, respiration, blood gas and lung function, improve clinical efficacy and reduce adverse reactions in the treatment of COPD with respiratory failure.

Key words： Chronic obstructive pulmonary disease Respiratory failure Low flow oxygen inhalation through nose Nasal high flow oxygen humidification therapy Curative effect

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	LI Xia
	WEI Qingmei
	CHEN Jianfeng

Cite this article:

LI Xia,WEI Qingmei,CHEN Jianfeng. Application Analysis of Nasal High Flow Oxygen Humidification Therapy in Patients with Chronic Obstructive Pulmonary Disease and Respiratory Failure[J]. HeBei Med, 2022, 28(1): 117-121.

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2022.01.024 OR http://www.hbyxzzs.cn/EN/Y2022/V28/I1/117

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