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| Effect of Two Different Surgical Methods on Functional Recovery and Serum IL-1 IL-17 and ESR in Elderly Patients with Knee Osteoarthritis |
| YANG Hui |
| Linfen Central Hospital, Shanxi Linfen 041000, China |
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Abstract Objective: To investigate the effect of two different surgical methods on functional recovery and serum IL-1, IL-17 and ESR in elderly patients with knee osteoarthritis (KOA). Methods: This study retrospectively reviewed 153 elderly patients with KOA admitted to the department of joint surgery in the hospital between January 2018 and December 2020. The patients were divided into unicompartmental knee arthroplasty group (n=76) and total knee arthroplasty group (n=77) according to the surgical method. The operation time, length of hospital stay, hospitalization expenses, interleukin-1 (IL-1), interleukin-17 (IL-17), erythrocyte sedimentation rate (ESR), knee society score (KSS), Hospital for Special Surgery (HSS) score, Lysholm knee score, and complications were compared between the two groups. Results: The operation time and hospital stay of the unicompartmental knee arthroplasty group were significantly shorter than those of the total knee arthroplasty group (P<0.05), but there was no statistical difference in hospitalization expenses between the two groups (P>0.05). There was no significant difference in IL-1, IL-17 and ESR between the two groups before surgery (P>0.05). After surgery, the levels of serum IL-1 and IL-17 were reduced in the two groups (P<0.01), but no significant change in ESR was found (P>0.05), without statistically significant difference between the two groups (P>0.05). There was no statistically significant difference in KSS score, HSS score and Lysholm knee score between the two groups before surgery (P>0.05). After surgery, the above scores of the two groups were increased (P<0.01), but there was no statistically significant difference between the two groups (P>0.05). The incidence of complications in the unicompartmental knee arthroplasty group was significantly lower than that in the total knee arthroplasty group (P<0.05). Conclusion: Unicompartmental knee arthroplasty has the advantages of short duration, short hospital stay, quick wound healing, and few complications.
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2021, Vol. 27 
