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Diagnostic Value of MRI and DCE-MRI in Ovarian Tumors and Tumor Like Lesions |
LU Longlong, WANG Dong, LIAN Peng, et al |
Xi'an People's Hospital/Xi'an Fourth Hospital, Shaanxi Xi'an 710004, China |
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Abstract Objective: To explore the diagnostic value of magnetic resonance imaging (MRI) and dynamic contrast-enhanced MRI (DCE-MRI) in ovarian tumors and tumor-like lesions. Methods: 81 patients with ovarian tumors (ovarian tumor group) and 132 patients with tumor-like lesions confirmed by surgical pathology (tumor-like lesion group) were enrolled in this study between December 2014-April 2021. The MRI and DCE-MRI data of the two groups of patients were collected and analyzed retrospectively. Results: Conventional MRI showed that the probabilities of irregular lesions, capsule wall>3.0mm, parenchyma>3.0mm, and massive pelvic effusion were greater in the ovarian tumor group than in the tumor-like lesion group (P<0.05). The largest diameter of the lesion in the ovarian tumor group was (12.30±3.68) cm, larger than (9.00±1.01) cm in the tumor-like lesion group (P<0.05). DCE-MRI showed that the volume transfer constant (Ktrans), extravascular extracellular volume fraction (Ve), and rate constant (Kep) of the region of interest (ROI) in the ovarian tumor group were greater than those in the tumor-like lesion group (P<0.05). The receiver operating characteristic (ROC) curve analysis showed that the sensitivity of MRI combined with DCE-MRI in differential diagnosis of ovarian tumors and tumor-like lesions was the highest, which was 93.83% (P<0.05). Youden index, area under the curve (AUC) and 95% CI were 0.757, 0.878, and 0.827 ~ 0.919. Conclusion: Both MRI and DCE-MRI have certain value in the diagnosis of ovarian tumors and tumor-like lesions, and the combination of the two has the highest value. Patients with ovarian tumors have more irregular lesions with thicker capsule walls, more parenchyma and larger diameters, more pelvic effusion, and larger Ktrans, Kep and Ve in DCE-MRI. In clinical practice, conventional MRI and functional MRI can be combined to differentiate benign and malignant ovarian lesions, thereby improving the accuracy and enable patients to receive treatment as soon as possible.
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[1] 王丹,代晶,潘长清,等.血清CA125、HE4以及ROMA指数在卵巢癌早期诊断中的应用价值[J].实用妇产科杂志,2018,34(4):80~82. [2] 魏明翔,柏根基,郭莉莉.影像组学在卵巢肿瘤中的研究进展[J].磁共振成像,2020,11(5):314~316. [3] 刘宇佳,陈亮,田春梅,等.巨大卵巢卵泡膜细胞瘤与阔韧带子宫肌瘤的MRI鉴别诊断[J].临床放射学杂志,2019,38(8):105~108. [4] 任鸿萍,洪莲,张毅辉,等.1.5T MRI弥散加权成像联合CT对女性盆腔肿瘤良恶性的诊断价值分析[J].影像科学与光化学,2020,38(3):154~158. [5] 徐慧婷,倪建明,韩翠平,等.靶向卵巢癌细胞荧光-磁共振双模态纳米探针的制备及细胞成像[J].中华核医学与分子影像杂志,2019,39(4):222~226. [6] 毛咪咪,冯峰,李海明.不同感兴趣区选择方法在上皮性卵巢癌动态增强MRI参数中一致性的比较[J].CT理论与应用研究,2019,28(2):87~95. [7] 陈炽翔,黄丹江.两种不同影像学方法对卵巢癌的诊断价值比较[J].中国妇幼健康研究,2019,30(10):41~44. [8] 邵建.常规磁共振成像联合弥散加权成像在卵巢癌腹膜转移诊断中的应用价值[J].河南医学研究,2021,30(12):2274~2276. [9] 璐芳,蔡晶,王泽华.VEGF及基质金属蛋白酶与卵巢癌临床分期的相关性分析[J].中南医学科学杂志,2019,47(1):30~32. [10] 王维平,张乐,李金星,等.常规MRI及DCE-MRI在卵巢肿瘤及肿瘤样病变诊断中的应用[J].中国医学计算机成像杂志,2020,26(1):39~44. |
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