自拟理机养阴通络汤联合针灸治疗缺血性脑卒中的效果及对颅内血流外周血APN ET及Cor水平的影响

doi:10.3969/j.issn.1006-6233.2021.05.028

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Abstract Objective: To explore the effects of self-made Liji Yangyin Tongluo decoction combined with acupuncture and moxibustion in the treatment of ischemic stroke (IS) and its influence on intracranial blood flow and levels of peripheral blood adiponectin (APN), endothelin (ET) and cortisol (Cor). Methods: 186 patients with IS were divided into control group and observation group according to the random number table method, with 93 cases in each group. Control group was treated with conventional western medicine combined with self-made Liji Yangyin Tongluo decoction, and observation group was added with acupuncture and moxibustion based on control group. After 30 d of treatment, the clinical efficacy, neurological function and motor function and quality of life, intracranial blood flow velocity and serum biochemical indicators were observed in the two groups. Results: The total effective rate of treatment was higher in observation group than in control group (90.32% vs 79.57%) (P<0.05). After treatment, the National Institutes of Health Stroke Scale (NIHSS) score in the two groups was significantly reduced while the Fugl-Meyer motor function scale score, modified Barthel index (MBI) score and stroke-specific quality of life scale (SS-QOL) score were significantly increased compared to before treatment, and the blood flow velocities of anterior cerebral artery (ACA), middle cerebral artery (MCA) and posterior cerebral artery (PCA) were obviously increased compared with those before treatment, and the level of APN was significantly lower than that before treatment while the levels of ET and Cor were markedly higher than those before treatment, and the changes in observation group were larger than those in control group (P<0.05). Conclusion: Self-made Liji Yangyin Tongluo decoction combined with acupuncture and moxibustion has significant efficacy in the treatment of IS, and it can significantly improve the neurological function, motor function and intracranial blood flow status.

Key words： Acupuncture and moxibustion Liji Yangyin Tongluo decoction Ischemic stroke Clinical efficacy

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2021.05.028 OR http://www.hbyxzzs.cn/EN/Y2021/V27/I5/831

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