合并室性心律失常的心衰患者病情严重程度与心率变异变化的相关性分析

doi:10.3969/j.issn.1006-6233.2021.04.025

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Abstract Objective: To analyze the correlation between the severity of heart failure and heart rate variability in patients with heart failure (hereinafter referred to as heart failure) with ventricular arrhythmia.Methods: 123 patients with heart failure and ventricular arrhythmia were selected prospectively as observation group, 30 patients without ventricular arrhythmia treated continuously in the same period were set as the control group. The basic diseases, NYHA cardiac function classification and left ventricular ejection fraction (LVEF) were compared between the two groups. The relationship between the severity of disease and heart rate variability (HRV) was analyzed based on the cardiac function classification. According to the follow-up results, the risk factors of cardiovascular composite endpoint events were analyzed. Results: In terms of HRV parameter time domain indexes (SDANN, SDNN Index, SDANN Index, RMSSD, PNN50) and frequency domain indexes (HF, LF, VLF), the indexes of the observation group were significantly lower than those of the control group (P<0.05). There were significant differences in the indicators of patients with different cardiac function classifications in the observation group (P<0.05). Among them, the HRV parameters of patients in grade Ⅳ were significantly lower than those in grades Ⅱ and Ⅲ (P<0.05). The classification showed a significant negative correlation (P<0.05). In terms of cardiovascular composite endpoint events, 68 cases (44.4%) occurred, combined ventricular arrhythmia occurred significantly more, and each HRV parameter index was significantly lower than the non-occurring group (P<0.05); COX analysis results showed that, SDANN Index, LF, and combined ventricular arrhythmia are risk factors (P<0.05). Conclusion: The severity of heart failure patients with ventricular arrhythmia is significantly negatively correlated with heart rate variability; SDANN index, LF, and ventricular arrhythmia are risk factors of cardiovascular composite endpoint events, HRV parameter detection could help to assess the condition and predict the prognosis, and the time period needed to be focused is 2-4 months after the first 12 lead Holter.

Key words： Heart failure Ventricular arrhythmia Classification of cardiac function HRV Risk factors

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2021.04.025 OR http://www.hbyxzzs.cn/EN/Y2021/V27/I4/644

[1] 徐晓蓉,平鹏娜,王欣,等.应用心力衰竭清单对慢性心力衰竭患者进行社区管理的效果研究[J].中国全科医学,2020,23(2):141~146.
[2] 吴杰.亚洲和中国心脏性猝死[J].中国心脏起搏与心电生理杂志,2017,31(3):189~191.
[3] 张懿,周洲.经皮冠状动脉介入治疗对冠心病患者的T波峰末间期的影响及心脏性猝死的预警价值[J].中国基层医药,2019,26(16):1947~1950.
[4] 许顶立,张昊.2019年欧洲心力衰竭协会/欧洲心脏病学会《射血分数保留的心力衰竭的诊断》解读[J].中国全科医学,2020,23(11):1327~1332.
[5] Marchitto N,Sindona F,Mobilia P,et al.Effect of low-dose sacubitril/valsartan on body composition,bioelectrical impedance analysis,heart rate variability and T-peak to T-end index in elderly patients with severe chronic heart failure: a pilot experience[J].Curr Med Res Opin,2019,35(sup1):13~15.
[6] 郭丹玲,胡红杰,赵振华,等.心肌瘢痕对慢性心肌梗死后恶性室性心律失常发生的预测价值[J].浙江大学学报(医学版),2019,48(5):511~516.
[7] 刘海菊,李小梅,戈海延,等.先天性长QT综合征并先天性完全性房室传导阻滞及恶性室性心律失常1例[J].中华实用儿科临床杂志,2018,33(18):1431~1432.
[8] 贾凯剑,郭任维,高胜利,等.红细胞分布宽度与慢性心力衰竭的相关性研究[J].中国现代医学杂志,2019,29(24):27~31.
[9] Besnier F,Labrunee M,Richard L,et al.Short-term effects of a 3-week interval training program on heart rate variability in chronic heart failure.A randomised controlled trial[J].Ann Phys Rehabil Med,2019,62(5):321~328.
[10] 卫洪超,顾承雄,于洋,等.心力衰竭力学机制研究[J].中华胸心血管外科杂志,2019,35(10):629~634.
[11] 李东明,尹兰,张超.Tp-e间期及Tp-e/QT联合诊断重度慢性心功能不全患者恶性室性心律失常的ROC曲线分析[J].海南医学,2018,29(11):1500~1503.
[12] 姚丽,张剑波,李永星,等.重组人B型钠尿肽对急性心肌梗死后心力衰竭患者心功能及心率变异性的影响[J].中国中西医结合急救杂志,2019,26(1):50~53.