右美托咪定预防小儿七氟醚麻醉苏醒期躁动的研究

doi:10.3969/j.issn.1006-6233.2021.04.014

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Abstract Objective: To investigate the role of dexmeditomidine (Dex) in preventing agitation during the resuscitation period of sevoflurane anesthesia in children.Methods: 100 cases of pediatric laparoscopic hernia surgery with sevoflurane anesthesia from January 2018 to January 2019 in our hospital were selected and sub-grouped into Dex group (n = 50) and control group (n = 50) according to admission sequence of odd or even numbers. Normal saline and Dex pump were administered to both groups. Incidence of restlessness and awakening time were recorded. Results: The incidence of agitation in the Dex group was 4.0%, lower than that in the control group (26.0%), and the difference was statistically significant (P<0.05).The scores of agitation and pain in the Dex group were lower than those in the control group when they were just admitted to the recovery room, 5 min after entry, 10 min after entry, and Ramsay sedation scores at 1-3 h after extubation were higher than those in the control group (P<0.05).There was no statistically significant difference between the two groups in the time of anesthesia recovery and time to leave the recovery room (P>0.05). Conclusion: Dex can prevent the occurrence of sevoflurane agitation during the awaking period of anesthesia in children and ensure the safety of surgery.

Key words： Dex meditomidine Sevoflurane Anesthesia Restlessness during awakening

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2021.04.014 OR http://www.hbyxzzs.cn/EN/Y2021/V27/I4/588

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