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| Predictive Value of Uterine Artery Blood Flow Parameters in Early Pregnancy on Adverse Pregnancy Outcomes in Patients with Recurrent Spontaneous Abortion |
| LU Wei, LIU Honghong, YANG Weihao, et al |
| Qingdao Hospital Affiliated to Shandong First Medical University, Shandong Qingdao 266109, China |
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Abstract Objective: To investigate the predictive value of ultrasound parameters of uterine artery in patients with recurrent spontaneous abortion (RSA) for pregnancy outcomes.Methods: 100 RSA patients with 6~10 weeks of pregnancy in our hospital from August 2016 to August 2019 were selected as the observation group, and 120 cases of normal pregnant women with 6~10 weeks of pregnancy were selected as the control group. The uterine artery hemodynamic parameters (PI, RI, S/D) of pregnant women were monitored by Doppler ultrasound. Receiver operating characteristic (ROC) curve was used to evaluate the diagnostic value of ultrasound parameters for adverse pregnancy outcomes. The relationship between ultrasound parameters and adverse pregnancy outcomes was analyzed by logistic regression. Results: The PI, RI and S/D value in RSA group were higher than those of control group (P<0.05). PI, RI, S / D, PI + RI, PI + S / D, RI + S / D and PI + RI + S / D had high sensitivity and specificity in predicting adverse pregnancy outcomes. The area under the curve (AUC) was 0.638, 0.801, 0.816, 0.832, 0.827, 0.881 and 0.962, respectively. PI, RI and S / D were high risk factors of adverse pregnancy (P<0.05). Conclusion: Compared with normal pregnant women, uterine artery Doppler ultrasound blood flow index of RSA patients in early pregnancy is higher, which has higher predictive value for adverse pregnancy.
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2021, Vol. 27 
