他汀类对AMI患者急诊经皮冠状动脉介入治疗术后血脂IL-6 TNF-α和血液粘度的影响

doi:10.3969/j.issn.1006-6233.2021.01.003

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Abstract Objective: To investigate the effects of statins on blood lipid, IL-6,TNF- α and blood viscosity after emergency percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI). Methods: A total of 100 patients with AMI treated in our hospital from December 2017 to August 2018 were randomly divided into two groups: control group (n = 50) and trial group (n = 50).The patients in both groups were treated with PCI and corresponding drug therapy. The blood lipid, IL-6,TNF- α and blood viscosity were measured and compared before and after treatment with rishovastatin in the groups. Results: After treatment, the level of IL-6,TNF- α in the two groups was lower than that before treatment, and that in the trial group was more obvious than that in the control group(P<0.05).The levels of blood lipid (HDL-C,LDL-C,TC,TG) were significantly improved in the treatment group than in the control group (P<0.05).After treatment, NBH and NBL in the two groups were lower than those before treatment, especially in the test group(P<0.05). Conclusion: After emergency PCI in patients with AMI, risuvastatin could significantly inhibit the level of IL-6,TNF- α and blood viscosity, and effectively improve the level of blood lipid.

Key words： Acute myocardial infarction Risuvastatin Blood lipid Blood viscosity Percutaneous coronary intervention

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	HAN Xue
	CHEN Lijie

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HAN Xue,CHEN Lijie. Effects of Statins on Blood Lipid IL-6 TNF- α and Blood Viscosity After Emergency Percutaneous Coronary Intervention in Patients with AMI[J]. HeBei Med, 2021, 27(1): 11-14.

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2021.01.003 OR http://www.hbyxzzs.cn/EN/Y2021/V27/I1/11

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