重症患者营养风险筛查及肠内肠外营养序贯治疗对临床结局的影响

doi:10.3969/j.issn.1006-6233.2020.06.031

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Abstract Objective: To investigate the effect of nutritional risk screening and sequential treatment of early enteral nutrition combined with parenteral nutrition for critical patients on clinical outcomes. Methods: A total of 137 critical patients admitted to the Intensive Care Unit from December 2017 to December 2018 were enrolled in the study. All of them were screened for nutritional risk. 90 patients with nutritional risk were divided equally into control group, which was treated with total parenteral nutrition, and the observation group, which was given early enteral nutrition combined with parenteral nutrition sequential treatment. The levels of albumin (ALB), prealbumin (PA) and transferrin (TRF) were measured at admission and 14 days after treatment. Total hospitalization cost, ICU stays and hospital stays were compared. The occurrence of complications in patients were observed and recorded. Results: The NRS 2002 average score of 90 patients with nutritional risk was (5.26±1.02), and thereinto, 47 patients had the score of (2.35±0.68). There was a significant difference between the groups (t=-17.607, P=0.000).14 days after treatment, the levels of ALB, PA and TRF were increased in both groups. There was significant difference between the groups (P<0.05).The total hospitalization cost, ICU stays and hospital stays of the observation group were lower than the control group (P<0.05). The complication rate of the control group was 55.56%, which was significantly higher than the observation group (28.89%, χ²=6.559, P=0.010).There was a significant difference in the incidence of infection and stress-induced hyperglycemia (P<0.05). Conclusion: Early enteral nutrition combined with parenteral nutrition sequential treatment for critical patients with nutritional risk can improve the nutritional status, restore gastrointestinal function, reduce the incidence of complications, and shorten the length of hospital stay.

Key words： Critical patients Nutritional risk screening Early enteral nutrition combined with parenteral nutrition Sequential therapy Clinical outcome

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2020.06.031 OR http://www.hbyxzzs.cn/EN/Y2020/V26/I6/1020

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