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| The Effect of Surgical Options on the Quality of Sexual Life and Pregnancy of Infertile Patients with Endometrial Polyp |
| LIU Jingjing, ZHANG Xiaoguang, YUAN Fengyun |
| Bozhou People's Hospital, Anhui Bozhou 236800, China |
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Abstract Objective: To observe the effect of different surgical methods on the quality of sexual life and pregnancy outcome of infertile patients with endometrial polyp (EP). Methods:A retrospective analysis was made, involving 106 EP infertility patients having hospitalized from May 2017 to August 2018 who were grouped according to the surgical protocol, 53 cases in each of the clamping group and the resection group. The clamping group demanded mechanical removal with hysteroscopic polyp clamp and the resection group demanded hysteroscopic endometrial polypectomy through electrosurgical. Endometrial thickness,menstrual hemorrhage map (PBAC) score, intrauterine cytokines [interleukin-1β(IL-1β), interferon gamma (IFN-γ), insulin-like growth factor-1(IGF-1)] level, quality of sexual life, recurrence rate at one year follow-up, and pregnancy outcome were compared between the two groups before and after surgery. Results:Three months after operation, the resection group was reported with the endometrial thickness smaller and the PBAC score lower than clamping group(P<0.05) ; Cytokines in the uterine fluid: Three months after operation, the resection group was reported with levels of IL-1β, IFN-γ, and IGF-1 in the uterine fluid lower than clamping group(P<0.05); Quality of sexual life: six months after operation, the resection group reported higher sexual satisfaction and weekly frequency of sexual life, shorter sexual arousal time and longer orgasm duration than clamping group(P<0.05);Recurrence rate: Nine and twelve months after operation, the resection group reported lower recurrence rate than the clamping group (P<0.05); Outcome of pregnancy: After 12 months of follow-up, the intrauterine pregnancy rate in the resection group (74.51%) was higher than that in the clamping group (52.00%) (P<0.05). Conclusion:Compared with hysteroscopic polypectomy,hysteroscopic endometrial polypectomy can significantly improve the endometrial thickness of EP infertile patients, reduce menstrual volume, improve the quality of sexual life and intrauterine pregnancy rate, and has higher safety.
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[1] Ngo YG,Fu HC,Chu LC,et al.Specific hysteroscopic findings can efficiently distinguish the differences between malignant and benign endometrial polyps[J].Taiwan Obstet Gynecol,2020,59(1):85~90.
[2] 周卓,丁岩.子宫内膜息肉恶变的研究进展[J].中国妇产科临床杂志,2018,19(3):287~288.
[3] 董欢,刘小奕,蔡彦卿,等.单发和多发EP患者息肉组织中ER、VEGF和TGF-β1表达的差异及预后分析[J].检验医学,2019,34(5):415~420.
[4] Balcacer P,Cooper KA,Huber S,et al.Magnetic resonance imaging features of endometrial polyps:,frequency of occurrence and interobserver reliability[J].Comput Assist Tomogr,2018,42(5):721~726.
[5] 夏美琪,桂涛,黄美华,等.子宫内膜息肉发病机制研究进展[J].广西医学,2019,41(15):1958~1961.
[6] 邓翠平,丁昭宁.宫腔镜下行电切除术与钳夹术治疗子宫内膜息肉不孕症80例的有效性比较[J].重庆医学,2018,47(21):2871~2872,2880.
[7] 孙宏,吴蕾.宫腔镜下子宫内膜息肉电切除术与子宫内膜息肉摘除加电凝术治疗子宫内膜息肉的疗效比较[J].安徽医学,2019,40(2):115~118.
[8] 秦娟,李海英,寇莉.组织 β-Catenin mRNA和IGF-1 mRNA检测在子宫内膜癌和子宫内膜息肉疾病鉴别诊断中的应用[J].临床和实验医学杂志,2017,16(5):468~471.
[9] 何红梅.血清IL-1Ra、IL-1β、TOS、TAS在多囊卵巢综合征不孕症患者中的表达及意义[J].中国妇幼保健,2018,33(7):1591~1593.
[10] 陈意儿,黄勇.子宫内膜息肉采用宫腔镜下电切术配合球囊压迫止血对其应激反应及血流动力学的影响[J].浙江创伤外科,2017,22(5):910~911. |
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2020, Vol. 26 
