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Study on the Effect of Perioperative Application of Cefotaxime Sodium on Infection in Emergency Trauma Patients |
TAN Jun, et al |
Minda Hospital Affiliated to Hubei University for Nationalities, Hubei Enshi 445000, China |
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Abstract Objective: To investigate the effect of cefotaxime sodium on the infection of patients with trauma in perioperative period. Methods: A total of 120 trauma patients admitted to the emergency department were enrolled between January 2016 and December 2018. They were simple random grouping into two groups according to the random number table: 60 patients in the control group underwent routine clinical therapy. 60 patients in the group were treated with cefotaxime sodium anti-infective treatment based on the same clinical routine treatment as the control group. The changes of body temperature, white blood cells and CRP were measured in the two groups. The clinical efficacy and infection rate of the two treatment methods were evaluated. And wound healing rate, the data results were processed using statistical software SPSS19.0. Results: The study showed that there were no differences in white blood cell and body temperature and CRP levels between the two groups (P>0.05). On the 3rd postoperative day, the body temperature, WBC and CRP levels of the two groups were lower than those before the operation, but the experimental group was significantly lower than the control group (P<0.05). Compared with the control group, the treatment efficiency of the experimental group was significantly better (95.00% vs 76.67%) (P<0.05). After treatment, the infection rate of the experimental group was 3.33%, which was significantly lower than 16.67% of the control group (χ2=5.926, P<0.05). After treatment, the grade A healing rate was 51.67%, the grade B healing rate was 43.33%, and the grade C healing rate was 5.00%. The grade A healing rate was 31.67%, and the grade B healing rate was 38.33%. The rate was 30.00%; the two groups were compared (U=2.395, P=0.031). Conclusion: In the treatment of infection in perioperative emergency trauma patients, cefotaxime sodium has significant effect and high safety.
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[1] 李进沛,肖磊.多发伤急救与急诊创伤救治模式的探讨[J].临床急诊杂志,2014,15(12):775~777. [2] 陆一鸣,於平.在我国建立创伤急救新模式已迫在眉睫[J].临床急诊杂志,2013,14(1):1~3. [3] 李永华,杨玉波,厉为良.应用肌松剂治疗严重创伤合并急性呼吸窘迫综合征14例临床分析[J].临床内科杂志,2014,31(11):771~772. [4] 田颖,张新蕾,王改先,霍云燕,张海军.急诊创伤患者血标本分离病原菌分布及其耐药性分析[J].中国消毒学杂志,2017,34(8):774~777. [5] 陈钢,张德意,程俊峰.急诊创伤手术切口感染的临床分析与预防研究[J].中华医院感染学杂志,2015,25(6):1344~1346. [6] 冯宇.抗感染治疗用于急诊外科创伤手术切口感染的临床效果[J].中国现代药物应用,2018,12(20):84~86. [7] 石荟,董宇超,韩一平,等.急性时相反应蛋白与小细胞肺癌预后相关分析研究[J].国际呼吸杂志,2013,33(4):245~249. [8] 徐爽,庄金宝,艾清,等.快速C反应蛋白联合血常规检测提高儿童上呼吸道感染诊断的临床价值[J].中国实验诊断学,2013,17(8):1474~1475. [9] 蔡壬辛,黄彬.革兰阴性细菌对碳青霉烯类抗生素耐药机制的研究进展[J].中国微生态学杂志,2013,25(5):612~616. [10] 付翔宇.急诊外科创伤手术切口感染1150例临床分析[J].河南医学研究,2017,26(18):3376~3377. [11] 邹道发,郑罡.头孢唑啉对急诊外科手术患者术后切口感染的疗效评价[J].抗感染药学,2016(4):921~922. |
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