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| Analysis on Effects and Clinical Efficacy of Laparoscopic Appendectomy on Nutritional Status and Inflammatory Response of Elderly Patients with Appendicitis |
| CUI Kai, ZHOU Zipeng |
| Qinhuangdao Workers' Hospital, Hebei Qinhuangdao 066200, China |
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Abstract Objective: To study the effects and clinical efficacy of laparoscopic appendectomy (LA) on nutritional status and inflammatory response of elderly patients with appendicitis. Methods: 80 elderly patients with appendicitis in our hospital from January 2017 to August 2018 were selected and divided into OA group and LA group according to the simple randomization, with 40 cases in each group. OA group was treated with OA, and LA group was treated with LA, and the two groups were observed until discharge. The levels of serum albumin, hemoglobin and serum total protein were measured before operation and at 3 d after operation in the two groups. Serum tumor necrosis factor (TNF-α), interleukin-6 (IL-6) and C-reactive protein (CRP) were measured before operation and at 3 d after operation were detected in the two groups. The perioperative indicators were counted in the two groups, and the first postoperative exhaust time, first feeding time, first ambulation time and hospital stay were counted in the two groups, and the incidence rate of postoperative complications during, follow-up was counted in the two groups. Results: On 3 d after operation, the levels of serum albumin, hemoglobin and serum total protein in LA group were higher than those in OA group (P<0.05). The levels of TNF-α, CRP and IL-6 in LA group were lower than those in OA group (P<0.05). The intraoperative blood loss and incision length in LA group were less than those in OA group (P<0.05). The first exhaust time, first feeding time, first ambulation time and hospital stay in LA group were shorter than those in OA group (P< 0.05). There was no significant difference in the incidence rate of postoperative complications between the two groups (P>0.05). Conclusions: LA is more beneficial to the recovery of elderly patients with appendicitis because of less trauma, and it can reduce inflammatory response and affect the nutritional status of patients.
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2020, Vol. 26 
