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| Efficacy of Sodium Creatine Phosphate in Treatment of Viral Myocarditis in Children and Its Effect on Myocardial Enzyme and Troponin Levels |
| MA Ke, KOU Yan, LU Rong, et al |
| Affiliated Hospital of Yan'an University, Shaanxi Yan'an 716000, China |
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Abstract Objective: To investigate the therapeutic effect of sodium creatine phosphate on viral myocarditis in children and the effect on myocardial enzyme and troponin level. Methods: 94 children with viral myocarditis admitted to our hospital between March 2017 and October 2018 were selected as the subjects of the study. With the consent of the family members of the children, the children were divided into control group and observation group by simple random digital table method. Routine treatment and routine treatment combined with sodium creatine phosphate therapy were performed respectively. The therapeutic effects of the two groups were compared, and the levels of myocardial enzymes and troponin were compared between the two groups. Results: The total effective rate of the observation group was higher than that of the control group (P<0.05), and the CK,CK-MB,LDH,AST level of the two groups decreased after treatment (P1 <0.01, P2 <0.01), and the total effective rate of the observation group was higher than that of the control group (P<0.05). The comparison between the two groups showed that there was no significant difference in myocardial enzyme level between the two groups before treatment (P>0.05). After treatment, the level of CK,CK-MB,LDH,AST in the observation group was lower than that in the control group, the difference was statistically significant (P<0.01), but there was no significant difference in the level of cTnI between the two groups before treatment (P>0.05). After treatment, the level of cTnI in the observation group was significantly lower than that in the control group. Conclusion: In the treatment of viral myocarditis in children, sodium creatine phosphate has obvious therapeutic effect, can effectively reduce the level of myocardial enzymes and troponin, improve the prognosis of children, and is worthy of clinical promotion.
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2020, Vol. 26 
