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| Features of Montreal Classification in 134 Cases with Crohn's Disease and Related Risk Factors of Poor Prognosis |
| ZHAO Jiaxiu |
| The Third Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Liaoning Shenyang 110003, China |
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Abstract Objective: To investigate the features of Montreal classification in 134 cases with Crohn's disease (CD) and related risk factors of poor prognosis. Methods: The clinical data of CD patients who were admitted to the hospital from July 2015 to February 2018 were retrospectively analyzed. Montreal classifying was performed on them. The clinical features of different classification patients were compared. The risk factors of prognosis were analyzed. Results: Among the 134 patients, there were 82 (61.19%) male, and 52 (38.81%) female, with male to female ratio of 1.58:1. The confirmed age was mainly on A2, accounting for 76.12%. The lesion location was mainly on L3, accounting for 55.22%. The disease behavior was mainly on B1 type, accounting for 67.91%. There were significant differences in disease behavior distribution among patients with different lesions location subtypes (P<0.05). The proportion of B1 type in L4 patients was significantly lower than that in other types, while proportion of B2 type was higher than that in other types. The proportion of B1 type in L3 patients was higher than that in other types, while proportion of B2 type was lower than that in other types. All patients were followed up. There were 56 cases with poor prognosis and 78 cases with good prognosis. Univariate analysis showed that perianal lesions and disease behavior were associated with prognosis of CD patients (P<0.05). Logistic multivariate analysis showed that perianal lesions, B2 and B3 types as disease behaviors were independent risk factors for poor prognosis of CD patients (P<0.05). Conclusion: There are certain differences in clinical features among patients with different Montreal classifications. The perianal lesions and disease behavior are closely related to poor prognosis of patients. Montreal classification can be applied as a reference index for disease assessment, diagnosis and prognosis judgement.
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2019, Vol. 25 
