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Analysis of Anxiety and Depression in Elderly Patients with Hypertension Complicated with Lacunar Infarction |
WANG Jing, SUN Yanbao, LIU Yancheng, et al |
Chengde Central Hospital, Hebei Chengde 067000, China |
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Abstract Objective: To explore the factor of anxiety and depression in hospitalized elderly hypertension patients combined with lacunar cerebral infarction. Methods: The Hamilton Anxiety Scale (HAMA-14 items) and Hamilton Depression Scale (HAMD-24 items) were used to assess the anxiety and depression status of 162 elderly patients with hypertension and lacunar infarction in Geriatrics Department of Chengde Central Hospital, and to analyze the influencing factors of anxiety and depression. Multivariate logistic regression was used to analyze the related risk factors. Results: The anxiety group and the depression group were compared with the control group, gender, smoking,and carotid plaque were statistically difference (P<0.05); diabetes, hyperlipidemia, hypoalbuminemia, frailty, and sleep quality were no statistical difference (P>0.05).The risk factors of anxiety included living hyperlipidemia (OR=2.799; 95% CI:1.180~6.638), hypoproteinemia (OR=11.271; 95% CI:1.269~10.084), frailty (OR=2.675; 95% CI:1.232~5.809), sleep disorder (OR=3.364; 95% CI:1.559~7.256). The risk factors of depression included living hyperlipidemia (OR=4.610; 95% CI:1.505~14.123), hypoproteinemia (OR=5.889; 95% CI:1.863~18.614), frailty (OR=4.024; 95% CI:1.674~9.672), sleep disorder (OR=17.405; 95% CI:6.847~44.243). Conclusions: Diabetes mellitus, hyperlipidemia, hypoproteinemia, weakness, sleep disorders in elderly hypertensive patients with lacunar infarction are more likely to develop anxiety and depression.
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