甲状腺微小乳头状癌术中冰冻病理诊断准确性分析及影响因素

doi:10.3969/j.issn.1006-6233.2019.06.043

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Abstract Objective: To analyze the accuracy of intraoperative frozen section pathological diagnosis of thyroid papillary micro carcinoma (PTMC), and to explore the influencing factors of frozen pathological diagnosis. Methods: 296 patients with thyroid diseases in our hospital from March 2015 to April 2018 were selected as the subjects, all the patients were diagnosed by pathological section of intraoperative frozen section and pathological diagnosis of postoperative paraffin section, the pathological diagnosis of postoperative paraffin section was the gold standard, the accuracy of pathological diagnosis of intraoperative frozen section was analyzed. Logistic regression analysis was used to explore the risk factors affecting the accuracy of intraoperative frozen pathological diagnosis. Results: 51 cases of PTMC patients were diagnosed with postoperative paraffin section, with a detection rate of 17.23%. 40 cases were diagnosed by intraoperative frozen section, the diagnostic rate was 78.43%, the misdiagnosis rate was 7.84%, the delayed diagnosis rate was 9.80%, the missed diagnosis rate was 3.92%, and there were no false positive cases. The diagnostic accuracy of intraoperative frozen section was significantly different in tumor size, capsular invasion and thyroid calcification (P<0.05). Logistic multivariate regression analysis showed that tumor size and capsular invasion were independent risk factors affecting the accuracy of intraoperative frozen section pathological diagnosis. Conclusion: Intraoperative frozen section is highly accurate in diagnosing PTMC, the accuracy of diagnosis is affected by tumor size and capsule invasion.

Key words： Papillary thyroid micro carcinoma Frozen section Paraffin section Accuracy Risk factors

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	FU Jinfeng
	YIN Xia
	JIANG Tao

Cite this article:

FU Jinfeng,YIN Xia,JIANG Tao. Analysis on Accuracy and Influencing Factors of Intraoperative Frozen Section Pathological Diagnosis of Thyroid Papillary Micro Carcinoma[J]. HeBei Med, 2019, 25(6): 1041-1044.

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2019.06.043 OR http://www.hbyxzzs.cn/EN/Y2019/V25/I6/1041

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