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| Influence on Enteral Nutrition for Adipokines in Patient with Early Acute Pancreatitis |
| LI Guanghui, LV Feifei |
| The Affiliated Hospital of Inner Mongolia Medical University, Inner Mongolia Hohhot 010000, China |
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Abstract Objective: To study the effect of enteral nutrition for adipokines (adiponectin, leptin, omentin, visfatin) in patient with early acute pancreatitis. Methods: A total of 90 patients with AP from Jan. 2015 to Dec. 2017 were randomised to EN (n=45) and nil-by-mouth (NBM, n=45). Blood samples were taken on the first 4d of admission and adipokine concentrations was determined by ELISA assays. A linear mixed model analysis was used to determine differences in adipokine concentrations between the two study groups. Results: The infectious rate in patients with AP was lower than those with NBM. Omentin and leptin concentrations were significantly higher in patients with EN compared with NBM across the first 4 d of admission(63.5ng/ml vs 42.7ng/ml,6.3ng/ml vs 3.7ng/ml,P<0.05, respectively).No significant difference in adiponectin and visfatin concentrations were observed between the two groups. Conclusions: EN decreases the infectious rate in AP patients and it also increases omentin and leptin levels in AP. Further study is needed to understand whether these adipokines are responsible for the therapeutic benefits of EN.
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. [J]. HeBei Med, 2019, 25(5): 859-861. |
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2019, Vol. 25 
