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| Risk Factors of Cardio-cerebrovascular Disease in MaintenanceHemodialysis Patients and its Impact on Short-term Prognosis |
| XUE Yahui, WANG Yi |
| Beijing Sixth Hospital, Beijing 100007, China |
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Abstract Objective: To explore the risk factors of cardiovascular and cerebrovascular diseases in patients with maintenance hemodialysis (MHD) and its influence on short-term prognosis. Methods: 98 patients with MHD in our hospital from March 2013 to June 2018 were selected as the study subjects. According to whether they were complicated with cardiovascular and cerebrovascular diseases, they were divided into concurrent group and non-concurrent group. The clinical information of patients was analyzed to find out the risk factors of cardiovascular and cerebrovascular diseases. The patients were followed up for 2 years, and their survival and prognosis were recorded. Results: 35 cases were included in the concurrent group, and the incidence of cardiovascular and cerebrovascular diseases was 35.71% in MHD patients. Univariate analysis showed that hypertension (χ2= 10.671, P = 0001), dialysis age (t = 4.519, P<0.001), UA level (t=21.992, P<0.001) were related factors of cardiovascular and cerebrovascular diseases in MHD patients, but not with sex, diabetes history, serum albumin, Scr, BUN, TG, TC, LDL-C, HDL-C and Hb levels. The difference was not statistically significant(P>0.05).The results of binary logistic regression analysis showed that hypertension history, long dialysis age and high UA level were risk factors for cardiovascular and cerebrovascular diseases in MHD patients(P<0.05).The 2-year survival rate of the concurrent group was significantly lower than that of the non-concurrent group (P<0.05). Conclusion: The prognosis of MHD patients complicated with cardiovascular and cerebrovascular diseases is poor. Hypertension history, long dialysis age and high UA level are risk factors for the occurrence of cardiovascular and cerebrovascular diseases in MHD patients.
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2019, Vol. 25 
