|
|
|
| Effects of Three Kinds of Metal Repair Materials on the Levels of Inflammatory Factors in Periodontal Tissues and Gingival Crevicular Fluid of Patients with Oral Prosthetics |
| ZHAO Hengyue, ZHOU Ying, CHEN Yijing, et al |
| Hubei Third People's Hospital of Jianghan University, Hubei Wuhan 430033, China |
|
|
|
|
Abstract Objective: To explore the effects of three kinds of metal repair materials on the levels of inflammatory factors in periodontal tissues and gingival crevicular fluid of patients with oral prosthetics. Methods: A total of 213 patients with anterior porcelain fused to metal (PFM) full crown repair were selected. According to the three PFM repair materials, they were divided into nichrome PFM group (group A, n=71) and cobalt-chromium alloy PFM group (group B, n=71) and gold deposition PFM group (group C, n=71). And they were given 6 months of effective follow-up after oral prosthesis. The periodontal tissues, gingival crevicular fluid (GCF), gingival crevicular depth (GCD), gingival index (GI), gingival probing depth (GCD), gingival index (GI), receptor activator of NF-kB ligand (RANKL), osteoprotegerin (OPG) and RANKL/OPG ratio were detected in the three groups before repair and after 6 months of repair. Results: After 6 months of repair, the gingival crevicular fluid (GCF) in group A was significantly increased (P<0.05), and the gingival crevicular depth (GCD) was significantly prolonged (P<0.05), and the gingival index (GI) was increased (P<0.05), and there were no significant differences between group A and group B at different time points (P>0.05), and the above indexes in groups B and C were significantly lower than those in group A (P<0.05). After 6 months of repair, the levels of interleukin-1β (IL-1β), interleukin-6 (IL-6) and matrix metalloproteinase-2 (MMP-2) in periodontal tissues and gingival crevicular fluid were increased significantly in the three groups (P<0.05), and the receptor activator of NF-kB ligand (RANKL), osteoprotegerin (OPG) and RANKL/OPG ratio were significantly increased (P<0.05), and the changes in group A were significantly greater than those in group B and C (P<0.05), and there were no significant differences between the two groups (P>0.05). Conclusions: Cobalt-chromium alloy and gold precipitation PFM have less irritation to periodontal tissues than nickel-chromium alloy PFM. Inflammatory reaction in gingival crevicular fluid and bone absorption in alveolar bone of patients are lighter than nickel-chromium alloy PFM, which is suitable for clinical promotion.
|
|
|
|
|
|
[1] 郭会平.两种桩核冠修复体治疗牙体缺损的临床效果观察[J].中国医疗美容,2017,7(1):46~48.
[2] 缪羽,王丽娟,谢学英.不同材料全冠修复体对牙周组织及龈沟液成分影响的研究[J].中华老年口腔医学杂志,2015,13(1):51~53.
[3] 王亚玲,曹直,占时霞.钴铬合金和金合金烤瓷全冠修复对龈沟液中AST、ALP、TNF-α和IL-8、GP-x、MDA水平的影响[J].海南医学院学报,2016,22(17):2069~2072.
[4] 刘芳,李雅娟,马永平,等.不同pH值与氟离子浓度对口腔常用金属修复材料电化学腐蚀的影响[J].北京口腔医学,2017,25(2):85~88.
[5] 孟晓慧,刘克礼,李培,等.后牙金铂合金全金属颈环烤瓷熔附金属全冠的应用价值[J].武警医学,2015,26(12):1203~1205.
[6] Eliseev EA,Semchenko AV,Fomichov YM,et al.Surface and finite size effects impact on the phase diagrams,polar,and dielectric properties of(Sr,Bi)Ta2O9 ferroelectric nanoparticles[J].Journal of Applied Physics,2016,119(20):184112~3168.
[7] 王燕鹏.不同类型金属烤瓷底冠对龈沟液肿瘤坏死因子α及白细胞介素-6的影响[J].安徽医学,2016,37(12):1565~1567. |
|
|
|
2019, Vol. 25 
