|
|
Study on the Correlation of TCM Syndrome Differentiation of Acute Exacerbation of COPD with Lung Function, Blood Gas Analysis and Dyspnea Scale |
ZHAO Na, QIAO Huiping, ZHANG Yulong |
Baoji Hospital of Traditional Chinese Medicine, Shaanxi Baoji 721000, China |
|
|
Abstract Objective:To study the correlation of TCM syndrome differentiation with lung function, blood gas analysis and dyspnea scale in patients with acute exacerbation of chronic obstructive pulmonary disease (COPD). Methods:A total of 120 patients with acute exacerbation of COPD who were admitted to the hospital from October 2017 to August 2018 were selected as study subjects. According to common TCM syndrome differentiation, the patients were divided into wind-cold attacking lung type (n=30), hot-heat obstructing lung type (n=30), phlegm-dampness obstructing lung type (n=30) and water attacking heart type (n= 30). The lung function [forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1)], blood gas indexes [partial pressure of blood oxygen (PO2), partial pressure of carbon dioxide (PCO2)]and dyspnea scale (MMRC) scores were determined and their correlation with TCM syndrome differentiation was analyzed. Results:The FEV1, FEVl/FVC and PO2 of wind-cold attacking lung type were significantly higher than those of the other three types while PCO2 and MMRC score were lower than those of the other three types (P<0.05). Conclusion: The pulmonary function, blood gas analysis and dyspnea manifestations of patients with acute exacerbation of COPD of different syndrome types are different, which can be used as an auxiliary index for the dialectical typing of TCM.
|
|
|
|
|
[1] 王旭东.脾多肽辅助治疗COPD急性加重期患者的临床效果及安全性探讨[J].北京医学,2016,11(18):138~139. [2] 钟云青,许光兰,翁惠.中医药治疗慢性阻塞性肺疾病急性加重期痰热蕴肺证的研究概况[J].陕西中医,2017,38(3):406~408. [3] 闫香桂,吴国芳,黄芬,等.中医药治疗稳定期慢性阻塞性肺疾病研究进展[J].中医学报,2016,31(9):1284~1288. [4] 王新杰.COPD急性加重期和稳定期患者的肺功能评估及其与血清促炎因子、趋化因子的相关性[J].海南医学院学报,2016,22(21):2629~2632. [5] 中华医学会呼吸病学分会慢性阻塞性肺疾病学组.慢性阻塞性肺疾病诊治指南(2007年修订版)[J].中华结核和呼吸杂志,2007,46(1):8~17. [6] 赵晓霞,郭义娟,秦玉玲.COPD急性加重期和稳定期睡眠质量及其与肺功能相关性探究[J].解放军预防医学杂志,2017,35(5):457~460. [7] Aahin H,Naz A,Varol Y,et al.The effect of obesity on dyspnea,exercise capacity,walk work and workload in patients with COPD[J].Tuberkuloz Ve Toraks,2017,65(3):202~209. [8] 魏睿. 慢性阻塞性肺疾病急性加重期不同证型与实验室指标相关性研究进展[J].国际中医中药杂志,2017,39(11):1044. [9] 揭祥,吴峰,吴思仿.COPD急性加重期并呼吸衰竭病人ELWI与ITBI及呼吸功能指标的相关性[J].齐鲁医学杂志,2017,41(2):195~197. [10] Milacic N,Milacic B,Milojkovic M,et al.Correlation of C-reactive protein and copd severity[J].Acta Clinica Croatica,2016,55(1):41. |
|
|
|