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| Effects of Ropivacaine combined with Different Doses of Sufentanil on Hemodynamics and Anesthetic Effect of Cesarean Section Women |
| ZHENG Junqi |
| Zaozhuang Hospital of Traditional Chinese Medicine, Shandong Zaozhuang 277000, China |
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Abstract Objective: To investigate the effect of ropivacaine combined with different doses of epidural sufentanil on hemodynamics and anesthetic effects in women undergoing cesarean section. Methods: 80 women undergoing cesarean section in the hospital during the period from May 2015 to October 2017 were selected as the subjects. They were randomly divided into the control group (given ropivacaine anesthesia), study group 1 (given ropivacaine combined with 2.5 μg of sufentanil anesthesia), study group 2 (given ropivacaine combined with 2.5 μg of sufentanil anesthesia) and study group 3 (given ropivacaine combined with 7.5 μg of sufentanil anesthesia), 20 cases in each group. Changes of hemodynamic parameters [systolic blood pressure (SBP), diastolic blood pressure (DBP)], anesthetic effects (duration of analgesia, time to the highest block level), maternal Bromage motor score, neonatal Apgar score and drug safety in all groups were observed. Results: There was no significant difference in SBP and DBP between groups before anesthesia (P>0.05). After anesthesia, the SBP and DBP of control group, study group 1 and study group 3 were increased significantly (P<0.05), but there was no obvious changes in SBP and DBP of study group 2 (P>0.05). The analgesic maintenance time of the control group, study group 1, study group 2 and study group 3 were significantly prolonged in turn, while the time to reach the highest block plane was shortened in turn (P<0.05). There was no significant difference in the Bromage exercise scores among the 4 groups (P>0.05). Only the Bromage exercise scores of study group 3 were significantly higher than those of the control group. The Apgar scores of the control group, study group 1, study group 2 and study group 3 were significantly decreased in turn (P<0.05). There was no significant difference in the incidence of adverse drug reactions among the four groups (P>0.05). Conclusion: Ropivacaine combined with 5.0 UG sufentanil epidural used in cesarean section can effectively improve the anesthetic effect and safety without increasing the influence on hemodynamics and maternal and infant outcomes.
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2019, Vol. 25 
