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| Value of Multiple b-value DWI combined with DCE-MRI in the Differential Diagnosis of Prostate Cancer and Benign Prostatic Hyperplasia |
| LI Peng, et al |
| Xi'an Medical University, Shaanxi Xi'an 710021, China |
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Abstract Objective: To explore the value of multiple dispersion sensitivity coefficient (b-value) diffusion-weighted imaging (DWI) combined with dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in the differential diagnosis of prostate cancer (PCa) and benign prostatic hyperplasia (BPH). Methods: The clinical data of 82 patients suspected as PCa (observation group) from January 2014 to March 2018 were retrospectively analyzed. Another 30 healthy examiners at the same time period were selected as control group. All patients and control group were given DWI and DCE-MRI. The DWI signal intensity value (SI) and apparent diffusion coefficient value (ADC) were evaluated at different b values, and the values of single DWI, single DCE-MRI and combined detection were compared in the differential diagnosis of prostate diseases. Results: The accuracy was the highest by DWI combined with DCE-MRI, and the accuracy was the lowest by DCE-MRI (P<0.05). The sensitivity was the highest by combined detection, and the sensitivity was the lowest by DCE-MRI (P>0.05). The specificity was the highest by combined detection, and was the lowest by DCE-MRI (P>0.05). There was no statistically significant difference in the specificity of PCa by multiple b-value DWI and DCE-MRI (P>0.05). The accuracy and sensitivity of PCa by multiple b-value DWI were higher than those by DCE-MRI (P>0.05). When b=800, 1000s/mm2, the SI of PCa was higher than that of BPH and normal prostate tissue while the ADC of PCa was lower than that of BPH and normal prostate tissue (P<0.05). There were no significant differences between BPH and normal prostate tissue in the SI and ADC (P>0.05). When b=800s/mm2, the PC and ADC of PCa, BPH and normal prostate tissue were higher than those when 1000s/mm2 (P<0.05). Conclusions: Multiple b-value DWI combined with DCE-MRI has good diagnostic efficiency in the differential diagnosis of PCa and BPH, and it is beneficial to improve the accuracy of clinical diagnosis.
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[1] 葛梦颍,张程达,侯全亮,等.良性前列腺增生主要影响因素的Meta分析[J].现代预防医学,2017,44(10):1902~1907.
[2] 叶定伟,朱耀.中国前列腺癌的流行病学概述和启示[J].中华外科杂志,2015,53(4):249~252.
[3] 姚雪艳.1.5TMR多b值DWI在前列腺中央腺体癌与良性前列腺增生鉴别诊断中的应用[J].中国数字医学,2017,12(5):97~99.
[4] 马向征,王世威,许茂盛,等.DCE-MRI联合DWI定量分析在前列腺癌诊断中的应用价值[J].浙江医学,2017,39(1):7~11.
[5] 魏逸,翟建.DWI在前列腺癌诊断中的价值及其ADC值与Gleason评分相关性研究[J].皖南医学院学报,2017,36(2):165~169.
[6] 曲源,任永芳,陈杰,等.探讨磁共振多b值扩散加权成像在前列腺病变中的应用价值[J].磁共振成像,2016,7(5):342~346.
[7] 王中娟,吴文娟,姜春娟,等.ADC值联合磁共振动态增强对前列腺癌伴发精囊腺侵犯的诊断价值[J].中国临床医学影像杂志,2018,29(2):102~104.
[8] 夏仕勇,陈兵,宋超.磁共振高b值弥散加权成像在筛查前列腺癌中的应用价值探讨[J].安徽医学,2018,39(6):742~744.
[9] 方孙福,周晓燕,罗朝军,等.动态增强MRI结合DWI对前列腺癌的诊断价值分析[J].医学影像学杂志,2017,27(1):186~188. |
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2019, Vol. 25 
