持续气道正压通气与常规手术治疗阻塞性睡眠呼吸暂停的疗效比较

doi:10.3969/j.issn.1006-6233.2018.10.027

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Abstract Objective: To compare the efficacy of continuous positive airway pressure and conventional surgery in the treatment of obstructive sleep apnea. Methods: 86 patients with obstructive sleep apnea were treated as the subjects. According to the random number table, the patients were randomly divided into the control group receiving conventional surgery, and the study group was treated with continuous positive airway pressure ventilation, with 43 cases in each group. The differences between the two groups before and after treatment were observed. Results: The apnea hypopnea index (ESS) score and apnea hypopnea index (AHI) in the two groups were significantly lower than those before treatment, and the lowset oxygen saturation (LSaO₂) was significantly higher than before the treatment (P<0.01), while there was no significant difference between the two groups before and after the treatment (all P>0.05). 1 month after treatment, the platelet (PLT) in the study group was significantly lower than that before treatment, while the control group was significantly higher than before treatment (P<0.01); there was no significant difference between the two groups before and after the treatment of antithrombin activity (AT:A), protein C activity (PC:A), and factor V coagulant activity (FV:C). The activity of coagulation factor II (F II: C) in the control group was significantly higher than that before treatment (P<0.01), but there was no significant change in the study group (P>0.05) before and after treatment. Conclusion: Continuous positive airway pressure ventilation and conventional surgery have both good clinical efficacy in patients with obstructive sleep apnea, but continuous positive airway pressure ventilation can improve the patients' coagulation system.

Key words： Obstructive sleep apnea Continuous positive airway pressure Routine surgery

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	LI Lihong
	BAI Lu

Cite this article:

LI Lihong,BAI Lu. Comparison on Effect of Continuous Positive Airway Pressure and Conventional Surgery in the treatment of Obstructive Sleep Apnea[J]. HeBei Med, 2018, 24(10): 1692-1695.

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2018.10.027 OR http://www.hbyxzzs.cn/EN/Y2018/V24/I10/1692

[1] 袁帅芳,李辉东,张培,等.高血压伴阻塞性睡眠呼吸暂停低通气综合征患者发生左室肥厚的危险因素分析[J].郑州大学学报(医学版),2018,53(3):385~388.
[2] Cetin S, Vural MG, Firat H, et al. Obstructive sleep apnea syndrome is associated with impaired pulmonary artery distensibility and right ventricular systolic dysfunction[J]. Turk Med Sci,2018,48(2):346~353.
[3] 阻塞性睡眠呼吸暂停与卒中诊治专家共识组.阻塞性睡眠呼吸暂停与卒中诊治专家共识[J].中华内科杂志,2014,53(8):657~664.
[4] McEvoy RD, Antic NA, Heeley E, et al. CPAP for prevention of cardiovascular events in obstructive sleep apnea[J]. N Engl Med, 2016, 375(10): 919~931.
[5] Franklin KA, Lindberg E. Obstructive sleep apnea is a common disorder in the population-a review on the epidemiology of sleep apnea[J].Thorac Dis, 2015, 7(8): 1311~1322.
[6] 刘福来,赵明莉.压塑成形口腔矫治器与CPAP治疗阻塞性睡眠呼吸暂停综合征的疗效比较[J].河北医学,2015,21(8):1388~1390.
[7] Heiser C, Knopf A, Hofauer B. Surgical anatomy of the hypoglossal nerve: A new classification system for selective upper airway stimulation[J]. Head Neck,2017,39(12):2371~2380.
[8] Korcarz CE, Benca R, Barnet JH, et al. Treatment of obstructive sleep apnea in young and middle‐aged adults: Effects of positive airway pressure and compliance on arterial stiffness, endothelial function, and cardiac hemodynamics[J].Am Heart Assoc, 2016, 5(4): e002930.
[9] 兰星,余晓曼,胡克,等.关于阻塞性睡眠呼吸暂停治疗方法的新探讨[J].国际呼吸杂志,2015,35(1):60~62.
[10] Mitchell RB, Garetz S, Moore RH, et al. The use of clinical parameters to predict obstructive sleep apnea syndrome severity in children: the Childhood Adenotonsillectomy (CHAT) study randomized clinical trial[J]. JAMA Otolaryngol Head Neck Surg, 2015, 141(2): 130~136.
[11] 王淑民.CPAP对妊高征合并OSAHS患者炎症因子平均动脉压的影响[J].河北医学,2017,23(7):1177~1180.
[12] Ramar K, Dort LC, Katz SG, et al. Clinical practice guideline for the treatment of obstructive sleep apnea and snoring with oral appliance therapy: an update for 2015: an American Academy of Sleep Medicine and American Academy of Dental Sleep Medicine clinical practice guideline[J].Clin Sleep Med, 2015, 11(7): 773~827.
[13] 高雪梅.CPAP及口腔矫治器均可降低阻塞性睡眠呼吸暂停患者的血压水平[J].循证医学,2017,17(5):273~275.
[14] Mokhlesi B, Grimaldi D, Beccuti G, et al. Effect of one week of 8-hour nightly continuous positive airway pressure treatment of obstructive sleep apnea on glycemic control in type 2 diabetes: a proof-of-concept study[J]. Am Respir Crit Care Med, 2016, 194(4): 516~519.