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| Cytogenetic Analysis of 1032 Male Infertility Patients |
| CHAI Beibei, HE Pei, WANG Huiying, et al |
| Medical College of Dali University, Yunnan Dali 671000, China |
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Abstract Objective: To investigate the detection rate and abnormal type of abnormal chromosome karyotype in infertile patients. Methods: 1032 infertile patients' peripheral blood lymphocytes were detected by G banding karyotype analysis. Results: 51 cases of chromosomal abnormalities were found in 1032 male patients, the detection rate was 4.94%. Among them, there are 3 cases of sex chromosomal abnormalities, 11 cases of autosmal abnormalities, 37 cases of chromosome polymorphism changed, the 37 cases state including 8 cases of sex chromosomal polymorphism changed and 29 cases of autosomal polymorphic changed. Most clinical manifestations are weak symptoms, azoospermia and spouse repeated abortion. Conclusion: In male infertility patients, not only need to carry out routine analysis of semen, but also carry their abnormal chromosomes or chromosome polymorphisms detected to prevent patients from transmitting these abnormal chromosomes to the next generation, resulting in its offspring of infertility.
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2017, Vol. 23 
