Abstract：Objective: To explore the anesthesia effects of propofol-ruifentanil and sevoflurane-ruifentanil druing the laparoscopic hysterectomy and the influence on pneumodynamics. Methods: 106 cases of patients with laparoscopic hysterectomy in our hospital were selected as the research object, and were divided into sevoflurane group (n=53) and propofol group (n=53) according to the random number table. Two groups were induced by ruifentanil anesthesia, propofol group was given propofol to maintain anesthesia, while sevoflurane group was treated with sevoflurane anesthesia. The effects of 2 groups were compared, and the changes of pneumodynamics indexes were compared between 2 groups. Results: There was no significant difference in anesthesia maintenance time between sevoflurane group and propofol group (P>0.05), but the spontaneous breathing recovery time, recovery time, extubation time, verbal response time, eye opening time of sevoflurane group were earlier than propofol group (P<0.01); compared with after intubation 5 min, Paw and PIP of 2 groups after pneumoperitoneum 10 min and after pneumoperitoneum 30 min significantly increased, Cdyn decreased significantly (P<0.01), and Paw of treatment group was lower than that of control group (P<0.05); there was no significant difference in Paw, PIP, Cdyn between 2 groups after pneumoperitoneum 5 min and after minintubation 5 min (P>0.05); There was no significant change in the BIS between 5 min after intubation and 5 min after pneumoperitoneum in both groups (P>0.05), but the BIS value in sevoflurane group was significantly higher than that in propofol group (P<0.01). There was no significant difference in the MAP, CO, SVR and ACI after intubation 5 min between the 2 groups (P>0.05), compared with after intubation 5 min, the MAP and SVR levels after pneumoperitoneum 10 minutes and after pneumoperitoneum 30 min increased significantly, the SVR significantly increased in 2 groups (P<0.01), the ACI of sevoflurane group was lower than that of propofol group (P<0.01); There was no significant difference in CO between 2 groups at different time points and between groups (P>0.05). Conclusion: Sevoflurane combined with remifentanil and propofol combined with remifentanil during laparoscopic hysterectomy has a same anesthesia time, and has effect on pneumodynamics after establishing pneumoperitoneum, but sevoflurane combined with remifentanil can make the patients in a shorter period of time to recover and restore consciousness, reduce lung injury, and the effect on hemodynamics was relatively small.
孙旺春. 丙泊酚或七氟醚复合瑞芬太尼麻醉对腹腔镜子宫全切术患者的麻醉效果[J]. 河北医学, 2018, 24(7): 1086-1090.
SUN Wangchun. Anesthesia Effects of Propofol-ruifendanil or Sevoflurane-ruifentanil during the Laparoscopic Hysterectomy. HeBei Med, 2018, 24(7): 1086-1090.
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2018, Vol. 24 
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