Abstract：Objective: To explore the effect of different bladder filling degree on target location in radiotherapy of cervical cancer patients, and to provide reference for clinical application. Methods: A total of 8 patients with cervical cancer who were treated in the first phase of IIB IIIB in our hospital from June 2016 to June 2017 were collected. CT scan was performed in the bladder filling, half filling and vacuity state respectively, and the location of the target area in the different filling states of the cervix and uterus was analyzed. Results: The relative displacement of cervix and uterus in the different filling state of the bladder chould lead to relative bone signs. The change of left and right direction was the smallest. The largest lesion of cervical lesion was 1.5mm. It changed greatly in the direction behind chest. With the increase of bladder capacity, the cervical lesions moved towards the back of the body. The maximum range was 19mm. In the head foot direction during bladder filling degree and half filling degree of the movement of the cervical lesions was statistically significant (P<0.05), at half filling degree and the degree of cervical lesions empty mobility was statistically significant (P<0.05), and with the increase of bladder filling degree of cervical lesions generally to the foot direction body displacement, maximum the amplitude of 18.6mm.The palace of the movement of the influence in the chest behind the relatively large, with the increase of bladder filling degree, the palace body generally to the dorsal movement of the body, the maximum amplitude was 21mm, relatively small in the direction of change, the maximum amplitude of 1.2mm and different degree of bladder filling in the head foot direction opposite to the movement of a body significantly, and increase with the degree of bladder filling, the palace body generally to the head direction of the body displacement, the maximum amplitude of 13mm. Conclusion: In the radiotherapy of cervical cancer, we need to consider the different degree of bladder filling to move the cervical and uterine body position, so as to reduce the deviation of target area and protect normal tissues.
[1] 郭振江,刘宗文,郑瑞锋,等.沉默单羧酸转运体4对宫颈癌Hela、Siha细胞增殖、侵袭迁移及调亡的影响[J].郑州大学学报(医学版),2018,53(3):354~359 [2] 张志安,易红艳.紫杉醇联合铂类新辅助化疗局部晚期宫颈癌效果及对Smac Survivin MMP-2表达的影响[J].河北医学,2018,24(3):385~389. [3] 李东方,肖凤仪,李波,等.伊立替康联合卡铂辅助化疗对宫颈癌患者血清叶酸和CA125水平的影响[J].河北医学,2017,23(5):790~793. [4] 杜欣欣,杨昊,张慧娟,等.子宫颈癌根治性放疗中不同体外照射技术联合三维近距离放疗的剂量学研究及临床观察[J].中华妇产科杂志,2017,52(10). [5] Jhingran A, Salehpour M, Sam M, et al. Vaginal motion and bladder and rectal volumes during pelvic intensity-modulated radiation therapy after hysterectomy[J]. International Journal of Radiation Oncology Biology Physics, 2012,82(1):256~262. [6] 毛睿,何艳芬,齐洪志,等.膀胱充盈状态对宫颈癌术后调强放疗靶区和危及器官的影响[J].中华实用诊断与治疗杂志,2013,27(8):794~796.
2018, Vol. 24 
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