Abstract:Objective: To analyze comparatively the diagnostic value of virtual touch tissue quantification (VTTQ) and transrectal ultrasonography (TRUS) in prostatic cancer. Methods: 78 cases of patients with Prostate disease received from January 2016 to September 2017, according to the result of transrectal prostate biopsy, it was divided into prostate hyperplasia group 46 cases and prostate cancer group 32 cases. In the same period, 35 healthy volunteers were included in the control group. All of them were examined by TRUS, at the same time, VTTQ was used to detect the shear wave velocity (SWV) of the prostate tissue, comparative analysis of the efficacy of VTTQ and TRUS in the diagnosis of prostate cancer. Results: The SWV in the prostate cancer group and the prostatic gland hyperplasia group and was significantly higher than that in the control group (P<0.05), the prostate cancer group was significantly higher than the prostatic gland hyperplasia group (P<0.05). When SWV=2.23m/s, the sensitivity, specificity and accuracy of VTTQ in the diagnosis of prostate cancer are 84.38%,86.96%,85.90%, the sensitivity, specificity and accuracy of TRUS in the diagnosis of prostate cancer are78.13%,65.22%,70.51%, there was no significant difference in the sensitivity of VTTQ and TRUS in the diagnosis of prostate cancer (P>0.05). The specificity and accuracy of VTTQ in the diagnosis of prostate cancer were significantly different from those in TRUS (P<0.05). Conclusion: Compared with TRUS, VTTQ has a better diagnostic value for the prostatic cancer, with higher diagnostic specificity and accuracy.