Abstract：Objective: To observe the analgesic effect of buprenorphine combined with femoral nerve block for the primary total knee arthroplasty (TKA) and the short-term postoperative rehabilitation. Methods: Sixty-three cases of total knee arthroplasty were retrospectively analyzed from June 2016 to June 2017. They were divided into two groups according to the method of femoral nerve anaesthetised. The patients in group A were given ropivacaine with the addition of 0.3 mg of buprenorphine. The patients in group B were given ropivacaine. Postoperative resting and activities of the visual Analogue Score(VAS)at 12、24、36、48、60、72 hours, the range of motion(ROM) in 7 days, the consumption of oxycodone acetaminophen in 3 days and the duration of the hospital stay were compared between two groups. Results: The resting state VAS in group A was significantly lower than that in group B at 12, 24, 36, 48 hours (P<0.05), and there was no significant difference in 60, 72 hours (P>0.05). The activities state VAS in group A was significantly lower than that in group B at 12, 24, 36, 48, 60, 72 hours (P<0.05); The consumption of oxycodone acetaminophen group A was significantly lower than group B in 1, 2 day and total consumption (P<0.05); The ROM of group A was significantly greater than that of group B in 7 days post-surgery (P<0.05); There was no significant difference in hospital stay between the two groups(P>0.05). Conclusion: The results showed that buprenorphine combined with femoral nerve block can improve the short-term analgesic effect and reduce the consumption of morphine drugs, which is beneficial to the functional exercise and rehabilitation of the patients.
崔明达, 蔡善保. 丁丙诺啡联合股神经阻滞对膝关节置换术后快速康复的影响[J]. 河北医学, 2017, 23(11): 1819-1822.
CUI Mingda, et al. Effect of Buprenorphine Combined with Femoral Nerve Block on Fast-track Surgery after Primary Total Knee Arthroplasty. HeBei Med, 2017, 23(11): 1819-1822.
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2017, Vol. 23 
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