Abstract：Objective: To compare the accuracy of renal dynamic imaging and chronic kidney disease epidemiology collaboration (CKD-EPI) equation in determining the stage of the patients with chronic kidney disease. Method: A total of 121 patients with chronic kidney disease (CKD) was enrolled, and all the glomerular filtration rate (GFR) of the patients were determined simultaneously by dual plasma sample clearance method, 99mTc-DTPA renal dynamic imaging method and CKD-EPI equation. The dual plasma sample clearance method was used as the reference standard. The accuracy of the other two methods in determining the stage of the chronic kidney disease was compared and the comparison was repeated based on difference stage. Results: The accuracy of renal dynamic imaging and the CKD-EPI equation was 65.29% and 84.29%, respectively (P=0.001＜0.05). The advantage of CKD-EPI equation was reflected equation was 65.29% and 84.29%, respectively (P=0.000＜0.05). The advantage of CKD-EPI equation was reflected equation was 65.29% and 84.29%, respectively (P=0.000＜0.05). The advantage of CKD-EPI equation was reflected mainly in the stage of CKD4 and CKD5 (P=0.016 and P=0.031, respectively), while there was no obviously significant difference in the other stages (all P>0.05). Conclusion: The CKD-EPI equation showed better performance in determining the stage of the patients with chronic kidney disease. So the CKD-EPI equation may be the priority in clinical practice because of the accuracy and the simplicity.
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2019, Vol. 25 
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