Evaluation of Left Ventricular Systolic Function in Patients with Ischemic Cardiomyopathy by Three-dimensional Speckle Tracking Imaging and its Relationship with the Serum NT-proBNP Level
LIN Wenhai, YE Tingfang, WU Deli
Shenzhen Luohu District People's Hospital / Shenzhen Fifth People's Hospital,Guangdong Shenzhen 518100, China
Abstract：Objective: To investigate the relationship between left ventricular systolic function in patients with ischemic cardiomyopathy (ICM) evaluated by three-dimensional speckle tracking imaging (3D-STI) and the serum N-terminal pro-brain natriuretic peptide (NT-proBNP) level. Methods: A total of 52 patients with ICM diagnosed in the hospital during the period from February 2015 to February 2018 were selected as the observation group, and 30 healthy volunteers were selected as the control group. The three-dimensional full-volume dynamic images of the left ventricle were obtained by 3D-STI, and they were sent to work station for off-line analysis. The left ventricular global longitudinal strain (GLS), left ventricular global circumferential strain (GCS), left ventricular global radial strain (GRS) and left ventricular global strain (GS) were calculated and compared between the two groups. The NT-proBNPlevels in both groups were measured by photo-chemistry and the relationship between left ventricular systolic function and NT-proBNP level in the observation group was analyzed. Results: GLS, GCS and GS in the observation group were significantly higher than those in the control group (P<0.05), while the GRS was significantly lower than the control group (P<0.05). Serum NT-proBNP levels were significantly higher than those in the control group (P<0.05). GLS, GCS and GS were positively correlated with the serum NT-proBNPlevel in the observation group (r=0.416, 0.387, 0.424, P<0.05), while GRS was negatively correlated with the serum NT-proBNP level (r=-0.496, P<0.05). Conclusion: 3D-STI can better evaluate the left ventricular systolic function in patients with ICM. GLS, GCS and GS are positively correlated with the serum NT-proBNP level, while GRS is negatively correlated with the serum NT-proBNP level. Therefore, the serum NT-proBNP level can be used as an auxiliary index for evaluating the left ventricular systolic function in
林文海, 叶庭芳, 吴德礼. 三维斑点追踪技术评价缺血性心肌病患者左心室收缩功能及与血清N末端脑利钠肽前体水平的关系[J]. 河北医学, 2019, 25(7): 1091-1094.
LIN Wenhai, YE Tingfang, WU Deli. Evaluation of Left Ventricular Systolic Function in Patients with Ischemic Cardiomyopathy by Three-dimensional Speckle Tracking Imaging and its Relationship with the Serum NT-proBNP Level. HeBei Med, 2019, 25(7): 1091-1094.
[1] 李锦绣,吴胜本,郭建峰.曲美他嗪治疗缺血性心肌病心力衰竭疗效观察[J].中华全科医学,2013,11(7):1122~1123. [2] 高德全,贾文芳,谢亚闯,等.经皮冠状动脉介入治疗急性前壁心肌梗死患者QRS波时限与左心室射血分数的关系[J].岭南心血管病杂志,2017,23(5):534~536. [3] 冉红,张平洋.超声三维斑点追踪技术应用研究的进展及前景[J].心血管病学进展,2013,34(2):194~199. [4] 张钊,宋晓瑾,白宗旭.常规抗缺血性心肌病药物联合前列地尔改善缺血性心脏病患者心功能效果及对BNP水平的影响研究[J].实用心脑肺血管病杂志,2015,23(4):146~147. [5] 郭薇,林建婷,卢荔红,等.三维超声斑点追踪成像评价冠心病患者左室收缩功能[J].中国超声医学杂志,2016,32(4):304~306. [6] 雷常慧,刘丽文,纳丽莎,等.三维斑点追踪技术评价肥厚型心肌病患者左心室整体应变的研究[J].中华超声影像学杂志,2014,23(5):377~382. [7] 周娟,朱文军,徐明民,等.三维斑点追踪成像技术评价慢性心力衰竭患者左心室收缩功能及收缩不同步性的价值[J].浙江医学,2016,38(17):1415~1418. [8] Maffessanti F, Nesser H J, Weinert L, et al. Quantitative evaluation of regional left ventricular function using three-dimensional speckle tracking echocardiography in patients with and without heart disease.[J]. American Journal of Cardiology,2009,104(12):1755~1762. [9] 汪彩英,林来红,张苗,等.超声三维斑点追踪技术评价冠心病患者左心室整体收缩功能的研究[J].中国医药导报,2013,10(31):100~103.
2019, Vol. 25 
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