Abstract：Objective: To observe the effects of different anesthesia methods on CRP and complement C3 and C4 in patients undergoing laparoscopic cholecystectomy. Methods: Patients with laparoscopic cholecystectomy treated in our hospital from March 2014 to June 2015 were observed. According to the methods of operation, All the cases were divided into general anesthesia group (45 cases) and general anesthesia combined with epidural anesthesia group (50 cases). Observed the level of CRP, stress indicators of the two groups, as well as the effects of complement C3, C4, compared the anesthesia effect of the two groups of patients. Results: The level of CRP and cortisol of the two groups before anesthesia had no significant difference, while general anesthesia group of these indicators in skin incision after 2h, 4h after the operation changes compared with the compound anesthesia group obviously, the difference was statistically significant (P < 0.05); There was no significant difference in the level of C3 and C4 between the two groups before and after anesthesia. The changes of 2h and 4h in the general anesthesia group were significantly higher than those in the combined anesthesia group, the difference was statistically significant (P<0.05); After surgery, the VAS score of the combined anesthesia group was lower than that of the general anesthesia group, and the Ramsay scores of the two groups were not significantly different. Conclusion: General anesthesia combined with epidural anesthesia can significantly reduce the stress reaction of patients, and has a good effect of anesthesia.
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2017, Vol. 23 
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