L<sub>4/5</sub>棘突间植入椎间融合器的稳定性及对相邻节段的生物力学特性和生物相容性的影响

doi:10.3969/j.issn.1006-6233.2017.11.005

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摘要 目的: 探讨L_4/5棘突间植入椎间融合器的稳定性及对相邻节段的生物力学特性与生物相容性的影响。方法: 采集18组新鲜成人冰冻脊柱标本,其中模拟L_4/5棘突间植入椎间融合器为研究组,而正常标本为对照组,两组各9例,两组标本进行编号后经棘突间弹性内植入并用固定器进行固定。结果: 研究组于各个植入处在前屈、中心压缩、侧屈及后伸下的应变变化均较对照组小(P均<0.05)。于施加最大载荷600N下,研究组椎体的角位移与线性位移在左侧屈、左旋转、前屈、后伸状态下均小于对照组(P均<0.05)。结论: L_4/5棘突间植入椎间融合器可有效改善伤椎的活动度,保留其稳定性,有助于减轻椎间盘应力。

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关键词 ：椎间融合器, 稳定性, 生物力学, 生物相容性

Abstract：Objective: To investigate the effects of stability of the L_4/5 lumbar, biomechanical properties and biocompatibility of adjacent segments for interspinous fusion cage. Methods: 18 fresh adult frozen spine specimens were collected, including L_4/5 lumbar for interspinous fusion cage as the study group, and normal specimens as the control group, with 9 specimens in each group. The specimens of two groups were numbered and implanted in vivo and fixed by fixators. Results: The strain changes in different implantation for anteflexion, center compression, lateroflexion and rear protraction in the study group were smaller than in the control group (P all<0.05). Under the maximum load of 600 N, the angular displacement and linear displacement in left lateral flexion, levorotation, anteflexion and rear protraction in the study group were lower than in the control group (P all<0.05). Conclusion: L_4/5 lumbar for interspinous fusion cage can effectively improve the vertebral activity and keep its stability, which is helpful to shorten the stress of the intervertebral disc.

Key words： Interspinous fusion cage Stability Biomechanics Biocompatibility

基金资助:莆田学院院内课题,(编号:闽莆院2014042)

通讯作者: 林国兵

引用本文:

洪志群, 叶薇, 林国兵. L_4/5棘突间植入椎间融合器的稳定性及对相邻节段的生物力学特性和生物相容性的影响[J]. 河北医学, 2017, 23(11): 1776-1778.
HONG Zhiqun, YE Wei, LIN Guobing. The Stability of L_4/5 Interspinous Interbody Fusion Cage and its Effects on Biomechanical Properties and Biocompatibility of Adjacent Segments. HeBei Med, 2017, 23(11): 1776-1778.

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http://www.hbyxzzs.cn/CN/10.3969/j.issn.1006-6233.2017.11.005 或 http://www.hbyxzzs.cn/CN/Y2017/V23/I11/1776

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