Abstract：Objective: To analyze the video-assisted thoracoscope technology in primary lung lobectomy and the influence on serum c-reactive protein (CRP) and interleukin 6 (IL-6). Methods: 106 cases of primary lung cancers according to the simple random number table method those patient was divided into the 50 cases of control group and 56 cases of research group, control group traditional thoracotomy lung resection, research group video-assisted thoracoscope lung resection, then operation index, CRP, IL-6, lung function before and after surgery,postoperative complications in both groups was compared. Results: The incision length, intraoperative blood loss, postoperative pain time, hospital stay was better than control group (P<0.05); operation time, number of lymph node cleaning of two groups was no difference (P>0.05). Before operation, CRP and IL-6 in both group was no significant difference (P>0.05). After treatment, CRP, IL-6, MVV, 1s forced expiratory volume (FEV1) and forced vital capacity (FVC) in both groups were statistically significant, indicating that there were differences in treatment methods between the control group and the research group (P<0.05). CRP, IL-6 and FEV1 in the research group were lower than those in the control group at 1d and 3d after surgery, while MVV, FEV1 and FVC were higher than those in the control group. There were statistically significant differences in CRP, IL-6, MVV, FEV1 and FVC between the two groups at different time points (P<0.05). The postoperative complication rate of research group was lower than the control group (P<0.05). Conclusion: The exact effect of video-assisted thoracoscope technology in primary lung resection of lung cancer, can achieve similar to traditional thoracotomy surgical operation effect, and inhibit the overexpression of serum CRP and Il-6 and facilitate the recovery of lung function.
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2019, Vol. 25 
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