加味秦艽鳖甲汤治疗2型糖尿病合并初治涂阳肺结核的临床疗效

doi:10.3969/j.issn.1006-6233.2017.12.048

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摘要 目的:观察加味秦艽鳖甲汤治疗2型糖尿病合并初治涂阳肺结核的临床疗效。方法:选取2型糖尿病合并初治涂阳肺结核患者300例,将其随机分为两组,对照组采用常规降糖、抗结核药物治疗,治疗组在对照组的基础上采用加味秦艽鳖甲汤口服并雾化吸入治疗,治疗6个月后评价临床疗效。结果:两组治疗6个月末FBG、2hPBG、HbA1c水平及咳嗽、咳痰、喘息、肺部啰音评分均低于治疗前,差异具有统计学意义(P<0.05),治疗组降低程度大于对照组,差异具有统计学意义(P<0.05);治疗组治疗6个月末痰菌转阴率、空洞闭合率、病灶有效吸收率及治愈率高于对照组,差异具有统计学意义(P<0.05)。结论:在常规降糖及抗结核治疗的基础上联合加味秦艽鳖甲汤治疗2型糖尿病合并初治涂阳肺结核,能够更好的控制血糖,促进痰菌转阴、病灶吸收及空洞闭合,改善咳嗽、咳痰、喘息、肺部啰音等临床症状,提高临床疗效。

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关键词 ：加味秦艽鳖甲汤, 2型糖尿病, 初治涂阳肺结核, 临床疗效

Abstract：Objective: To observe the clinical efficacy of jiawei qinjiao biejia decoction in the treatment of type 2 diabetes mellitus combined with newly diagnosed smear-positive pulmonary tuberculosis. Methods: 300 patients with type 2 diabetes mellitus complicated with newly diagnosed smear-positive pulmonary tuberculosis were randomly divided into two groups. The control group was treated with conventional hypoglycemic and anti-tuberculosis drugs. The treatment group was treated on the basis of the control group jiawei qinjiao biejia decoction and aerosol inhalation treatment, 6 months after treatment to evaluate the clinical efficacy. Results: The levels of FBG, 2hPBG, HbA1c and cough, sputum, wheezing and pulmonary rales in the two groups were lower than those in the control group, the difference was statistically significant (P<0.05), and the treatment group was lower than the control group, the difference was statistically significant (P<0.05). The effective rate of wound healing, cure rate and cure rate were higher in the treatment group than in the control group, the difference was statistically significant (P<0.05). Conclusion: The combination of jiawei qinjiao biejia decoction in the treatment of type 2 diabetes mellitus combined with newly diagnosed smear-positive pulmonary tuberculosis can better control blood sugar, promote sputum negative, lesion absorption and empty closure, and improve cough, sputum, wheezing, lung rales and other clinical symptoms, improve clinical efficacy.

Key words： Jiawei qinjiao biejia decoction Type 2 diabetes mellitus Newly diagnosed smear positive pulmonary tuberculosis Clinical efficacy

基金资助:河北省中医药管理局科研计划项目,(编号:2015064)

通讯作者: 田彦卿

引用本文:

王岫峥,张皓,刁丽丽,王栋,李蕊,赵磊,田彦卿. 加味秦艽鳖甲汤治疗2型糖尿病合并初治涂阳肺结核的临床疗效[J]. 河北医学, 2017, 23(12): 2092-2095.
WANG Xiuzheng, ZHANG Hao, DIAO Lili, et al. Clinical Efficacy on Treatment of Type 2 Diabetes Mellitus Combined with Primary Treatment of Pulmonary Tuberculosis with Jiawei qinjiao biejia Decoction. HeBei Med, 2017, 23(12): 2092-2095.

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http://www.hbyxzzs.cn/CN/10.3969/j.issn.1006-6233.2017.12.048 或 http://www.hbyxzzs.cn/CN/Y2017/V23/I12/2092